ELECTROPHORESIS OF THE COMPLEMENT-FIXING ANTIGEN OF HUMAN INFLUENZA VIRUS.

The Journal of experimental medicine ·Vol. 72 ·No. 1 ·1940-06-30 ·Pages 11-9

Bourdillon J, Lennette EH

Abstract

1. An electrophoretic study has been made of normal mouse serum, influenza mouse serum, and influenza mouse lung suspension. The mobilities of the protein fractions present have been determined at various pH's by the optical method. 2. The pH-mobility curve of the soluble (complement-fixing) antigen present in the lung suspension has been determined analytically by sampling and application of the complement fixation test. The results show that the complement-fixing antigen has a mobility definitely smaller than that of serum albumin and close to that of a globulin, with an isoelectric point close to pH 5.

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Bourdillon J

Laboratories of the International Health Division of The Rockefeller Foundation, New York.

Lennette E H

References (8)

8 references, click to expand

ELECTROPHORETIC ANALYSIS OF PLASMA AND URINARY PROTEINS.
J Clin Invest. 1940 Mar;19(2):313-20 PMID: 16694748
IMMUNOLOGICAL AND CHEMICAL INVESTIGATIONS OF VACCINE VIRUS : VI. ISOLATION OF A HEAT-STABLE, SEROLOGICALLY ACTIVE SUBSTANCE FROM TISSUES INFECTED WITH VACCINE VIRUS.
J Exp Med. 1937 Jan 31;65(2):243-9 PMID: 19870598
Electrophoresis of serum globulin: Electrophoretic analysis of normal and immune sera.
Biochem J. 1937 Sep;31(9):1464-77 PMID: 16746478
A SOLUBLE ANTIGEN OF LYMPHOCYTIC CHORIOMENINGITIS : II. CHARACTERISTICS OF THE ANTIGEN AND ITS USE IN PRECIPITIN REACTIONS.
J Exp Med. 1940 Jan 1;71(1):43-53 PMID: 19870943
ELECTROPHORETIC PATTERNS OF NORMAL AND PATHOLOGICAL HUMAN BLOOD SERUM AND PLASMA.
J Exp Med. 1939 Sep 30;70(4):399-413 PMID: 19870918
IMMUNOLOGICAL REACTIONS WITH A VIRUS CAUSING PAPILLOMAS IN RABBITS : III. ANTIGENICITY AND PATHOGENICITY OF EXTRACTS OF THE GROWTHS OF WILD AND DOMESTIC SPECIES: GENERAL DISCUSSION.
J Exp Med. 1938 Oct 31;68(5):737-59 PMID: 19870814
Electrophoresis of human blood plasma: Electrophoretic properties of fibrinogen.
Biochem J. 1938 Apr;32(4):714-8 PMID: 16746678
INFECTIOUS MYXOMATOSIS OF RABBITS : PREPARATION OF ELEMENTARY BODIES AND STUDIES OF SEROLOGICALLY ACTIVE MATERIALS ASSOCIATED WITH THE DISEASE.
J Exp Med. 1937 Jun 30;66(1):1-14 PMID: 19870643

Article Info

Journal

The Journal of experimental medicine

Abbr.

J Exp Med

ISSN

0022-1007

DOI

10.1084/jem.72.1.11

Published

1940-06-30

Pages

11-9

Language

English

Region

United States

NLM ID

2985109R

PMCID

PMC2135010

External Links

PubMed source DOI: 10.1084/jem.72.1.11 PMC Full Text View journal details

Analysis Services

ELECTROPHORESIS OF THE COMPLEMENT-FIXING ANTIGEN OF HUMAN INFLUENZA VIRUS.

Contact

WeChat Official Account