UNION IN VITRO OF THE PAPILLOMA VIRUS AND ITS ANTIBODY.
Experiments are described which show that the rabbit papilloma virus elicits an antibody of one type only, this being capable both of neutralizing the virus and of fixing complement in mixture with it. The virus and its antibody have a powerful, specific affinity for one another, each being capable of absorbing the other in great excess when they are brought together in the test tube. The union formed by them in vitro cannot be dissociated in any demonstrable degree by dilution or centrifugation. In many respects the findings differ from those with most viruses previously studied.
9 references, click to expand
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ANTIRABIC IMMUNIZATION WITH CULTURE VIRUS RENDERED AVIRULENT BY ULTRA-VIOLET LIGHT.Science. 1937 Nov 12;86(2237):447-8 PMID: 17838963
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THE MASKING EFFECT OF EXTRAVASATED ANTIBODY ON THE RABBIT PAPILLOMA VIRUS (SHOPE).J Exp Med. 1939 Nov 30;70(6):583-604 PMID: 19870932
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INFECTIOUS PAPILLOMATOSIS OF RABBITS : WITH A NOTE ON THE HISTOPATHOLOGY.J Exp Med. 1933 Oct 31;58(5):607-24 PMID: 19870219
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STUDIES ON THE SOLUBLE PRECIPITABLE SUBSTANCES OF VACCINIA : II. THE SOLUBLE PRECIPITABLE SUBSTANCES OF DERMAL VACCINE.J Exp Med. 1936 Oct 31;64(5):819-30 PMID: 19870571
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IDENTITY OF "INHIBITOR" AND ANTIBODY IN EXTRACTS OF VIRUS-INDUCED RABBIT PAPILLOMAS.J Exp Med. 1940 Jul 31;72(2):175-200 PMID: 19871016
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A QUANTITATIVE STUDY OF THE PRECIPITIN REACTION BETWEEN TYPE III PNEUMOCOCCUS POLYSACCHARIDE AND PURIFIED HOMOLOGOUS ANTIBODY.J Exp Med. 1929 Nov 30;50(6):809-23 PMID: 19869667
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A TRANSPLANTABLE RABBIT CARCINOMA ORIGINATING IN A VIRUS-INDUCED PAPILLOMA AND CONTAINING THE VIRUS IN MASKED OR ALTERED FORM.J Exp Med. 1940 May 31;71(6):813-38 PMID: 19871000
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IMMUNOLOGICAL REACTIONS WITH A VIRUS CAUSING PAPILLOMAS IN RABBITS : III. ANTIGENICITY AND PATHOGENICITY OF EXTRACTS OF THE GROWTHS OF WILD AND DOMESTIC SPECIES: GENERAL DISCUSSION.J Exp Med. 1938 Oct 31;68(5):737-59 PMID: 19870814
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CANCERS DERIVING FROM THE VIRUS PAPILLOMAS OF WILD RABBITS UNDER NATURAL CONDITIONS.J Exp Med. 1940 Mar 31;71(4):469-94 PMID: 19870976
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