AN IMMUNOLOGICAL AND ELECTROPHORETIC COMPARISON OF THE ANTIBODY TO C POLYSACCHARIDE AND THE C-REACTIVE PROTEIN OF ACUTE PHASE SERUM.
1. Studies of the precipitation reaction of C polysaccharide with C protein, and of C polysaccharide with C antibody are reported. The similarity between these two systems in this respect is demonstrated. 2. The differences between C protein and C antibody are emphasized. The differences between this protein and antibodies in general have been reported previously by others. 3. Electrophoretic studies show that C antibody is in the gamma globulin fraction of serum whereas C protein migrates with the alpha(1) globulin fraction of acute phase protein.
8 references, click to expand
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THE OCCURRENCE DURING ACUTE INFECTIONS OF A PROTEIN NOT NORMALLY PRESENT IN THE BLOOD : I. DISTRIBUTION OF THE REACTIVE PROTEIN IN PATIENTS' SERA AND THE EFFECT OF CALCIUM ON THE FLOCCULATION REACTION WITH C POLYSACCHARIDE OF PNEUMOCOCCUS.J Exp Med. 1941 Jan 31;73(2):173-82 PMID: 19871070
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QUANTITATIVE STUDIES ON ANTIBODY PURIFICATION : I. THE DISSOCIATION OF PRECIPITATES FORMED BY PNEUMOCOCCUS SPECIFIC POLYSACCHARIDES AND HOMOLOGOUS ANTIBODIES.J Exp Med. 1936 Jul 31;64(2):161-72 PMID: 19870527
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THE OCCURRENCE DURING ACUTE INFECTIONS OF A PROTEIN NOT NORMALLY PRESENT IN THE BLOOD : III. IMMUNOLOGICAL PROPERTIES OF THE C-REACTIVE PROTEIN AND ITS DIFFERENTIATION FROM NORMAL BLOOD PROTEINS.J Exp Med. 1941 Jan 31;73(2):191-200 PMID: 19871072
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THE OCCURRENCE DURING ACUTE INFECTIONS OF A PROTEIN NOT NORMALLY PRESENT IN THE BLOOD : II. ISOLATION AND PROPERTIES OF THE REACTIVE PROTEIN.J Exp Med. 1941 Jan 31;73(2):183-90 PMID: 19871071
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QUANTITATIVE EXPERIMENTS WITH ANTIBODIES TO A SPECIFIC PRECIPITATE. I.J Exp Med. 1941 Jan 1;73(1):125-40 PMID: 19871062
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ELECTROPHORETIC PATTERNS OF NORMAL AND PATHOLOGICAL HUMAN BLOOD SERUM AND PLASMA.J Exp Med. 1939 Sep 30;70(4):399-413 PMID: 19870918
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CHEMICAL STUDIES ON BACTERIAL AGGLUTINATION : IV. QUANTITATIVE DATA ON PNEUMOCOCCUS R (DAWSON S)- ANTI-R (S) SYSTEMS.J Exp Med. 1938 Mar 31;67(4):545-50 PMID: 19870739
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SEROLOGICAL REACTIONS IN PNEUMONIA WITH A NON-PROTEIN SOMATIC FRACTION OF PNEUMOCOCCUS.J Exp Med. 1930 Sep 30;52(4):561-71 PMID: 19869788
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