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PMID: 19871420 Published · ppublish English Journal Article

KINETICS OF LYSIS BY CLOSTRIDIUM SEPTICUM HEMOLYSIN.

The Journal of experimental medicine ·Vol. 80 ·No. 4 ·1944-10-01 ·Pages 333-9

Bernheimer AW

Abstract

The kinetics of the hemolytic reaction effected by the hemolysin of Clostridium septicum, strain 44, has been studied with regard to the effect of concentration, temperature, and hydrogen ion concentration on the rate of the hemolytic reaction. The kinetics of hemolysis was found to resemble in several respects that of enzyme-catalyzed reactions, but differed in the absence of a clearly defined pH optimum. Attention is drawn to differences between the hemolytic system studied and certain other hemolytic systems.

Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Bernheimer A W
Department of Bacteriology, New York University College of Medicine, New York.
References (4)
4 references, click to expand
  1. Purification and properties of a haemolysin produced by group A haemolytic streptococci (streptolysin O).
    Biochem J. 1941 Nov;35(10-11):1124-39 PMID: 16747398
  2. The biochemistry of bacterial toxins: The lecithinase activity of Cl. welchii toxins.
    Biochem J. 1941 Sep;35(8-9):884-902 PMID: 16747456
  3. PARALLELISM IN THE LETHAL AND HEMOLYTIC ACTIVITY OF THE TOXIN OF CLOSTRIDIUM SEPTICUM.
    J Exp Med. 1944 Oct 1;80(4):309-20 PMID: 19871418
  4. NUTRITIONAL REQUIREMENTS AND FACTORS AFFECTING THE PRODUCTION OF TOXIN OF CLOSTRIDIUM SEPTICUM.
    J Exp Med. 1944 Oct 1;80(4):321-31 PMID: 19871419
Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
Published
1944-10-01
Pages
333-9
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2135470
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