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PMID: 19871686 Published · ppublish English Journal Article

STUDIES ON A LUNG TISSUE COMPONENT WHICH COMBINES WITH PNEUMONIA VIRUS OF MICE (PVM).

The Journal of experimental medicine ·Vol. 86 ·No. 5 ·1947-10-31 ·Pages 393-407

Volkert M, Horsfall FL

Abstract

Evidence has been obtained which indicates that the lung tissues of mammalian species susceptible to infection with PVM contain a specific component which combines with the virus. The concentration of this tissue component appears to be directly proportional to the suceptibility of the species; in its absence infection with PVM cannot be established. The available evidence suggests that the presence of the virus-combining component in lung tissue may play a decisive ro1e in the initiation of infection with this pneumotropic virus.

Keywords
LUNG/tissue component combining with pneumonia virus
MeSH Terms
Animals Lung Mice Murine pneumonia virus Pneumonia
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Volkert M
Hospital of The Rockefeller Institute for Medical Research.
Horsfall F L
References (6)
6 references, click to expand
  1. STUDIES ON PNEUMONIA VIRUS OF MICE (PVM) : II. IMMUNOLOGICAL EVIDENCE OF LATENT INFECTION WITH THE VIRUS IN NUMEROUS MAMMALIAN SPECIES.
    J Exp Med. 1946 Jan 1;83(1):43-64 PMID: 19871515
  2. STUDIES ON PNEUMONIA VIRUS OF MICE (PVM) : III. HEMAGGLUTINATION BY THE VIRUS; THE OCCURRENCE OF COMBINATION BETWEEN THE VIRUS AND A TISSUE SUBSTANCE.
    J Exp Med. 1946 Jan 31;83(2):105-32 PMID: 19871517
  3. A LATENT VIRUS IN NORMAL MICE CAPABLE OF PRODUCING PNEUMONIA IN ITS NATURAL HOST.
    J Exp Med. 1940 Feb 29;71(3):391-408 PMID: 19870970
  4. CENTRIFUGATION STUDIES ON PNEUMONIA VIRUS OF MICE (PVM) : THE RELATIVE SIZES OF FREE AND COMBINED VIRUS.
    J Exp Med. 1947 Jan 1;85(1):23-38 PMID: 19871597
  5. THE EFFECT OF SULFHYDRYL GROUPS ON PNEUMONIA VIRUS OF MICE (PVM).
    J Exp Med. 1947 Oct 31;86(5):383-91 PMID: 19871685
  6. STUDIES ON PNEUMONIA VIRUS OF MICE (PVM) : I. THE PRECISION OF MEASUREMENTS IN VIVO OF THE VIRUS AND ANTIBODIES AGAINST IT.
    J Exp Med. 1946 Jan 1;83(1):25-42 PMID: 19871514
Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
Published
1947-10-31
Pages
393-407
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2135743
Subset
OM
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