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PMID: 201539 Published · ppublish English Journal Article

Properties of a transposon conferring resistance to penicillins and streptomycin.

Gene ·Vol. 1 ·No. 3-4 ·1977-05-00 ·Pages 241-53

Hedges RW, Matthew M, Smith DI, Cresswell JM, Jacob AE

Abstract

R938 carries a transposon (TAbeta) of approximate molecular weight 9.5 Megadaltons (Mdal, 10(6) daltons). This contains genes for a beta lactamase of type TEM-1 and for streptomycin phosphatransferase (SPT). There is a ten-fold difference in the efficiency of transposition in different strains of E. coli K12.

MeSH Terms
Chromosomes, Bacterial Conjugation, Genetic DNA, Bacterial/isolation & purification Escherichia coli/enzymology,genetics Penicillinase/genetics Penicillins/pharmacology Phosphotransferases/genetics R Factors Streptomycin/pharmacology
Chemicals
DNA, Bacterial Penicillins Phosphotransferases Penicillinase Streptomycin
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Hedges R W
Matthew M
Smith D I
Cresswell J M
Jacob A E
Article Info
Journal
Gene
Abbr.
Gene
ISSN
0378-1119
DOI
10.1016/0378-1119(77)90048-8
Published
1977-05-00
Pages
241-53
Language
English
Region
Netherlands
NLM ID
7706761
Subset
IM
External Links
PubMed source DOI: 10.1016/0378-1119(77)90048-8 View journal details
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