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PMID: 20178858 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

The hygiene hypothesis: an evolutionary perspective.

Microbes and infection ·Vol. 12 ·No. 6 ·2010-06-00 ·Pages 421-7

Sironi M, Clerici M

Abstract

The hygiene hypothesis relies on the assumption that humans have adapted to a pathogen-rich environment that no longer exists in industrialized societies. Recent advances in molecular immunology and population genetics allow deeper insight into the evolution and co-evolution of host-pathogen interactions and, therefore, into the foundations of the hygiene hypothesis.

MeSH Terms
Biological Evolution Genetics, Population Host-Pathogen Interactions Humans Hygiene Selection, Genetic
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Sironi Manuela
Scientific Institute IRCCS E. Medea, Bioinformatics, Via don L. Monza 20, 23842 Bosisio Parini (LC), Italy. [email protected]
Clerici Mario
Article Info
Journal
Microbes and infection
Abbr.
Microbes Infect
ISSN
1769-714X
DOI
10.1016/j.micinf.2010.02.002
Email
[email protected]
Published
2010-06-00
Epub
2010-00-21
Pages
421-7
Language
English
Region
France
NLM ID
100883508
Subset
IM
External Links
PubMed source DOI: 10.1016/j.micinf.2010.02.002 View journal details
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