Membrane curvature in synaptic vesicle fusion and beyond.

Cell ·第 140 卷 ·第 5 期 ·2010-03-30

McMahon Harvey T, Kozlov Michael M, Martens Sascha

摘要

Recent evidence suggests that the Ca(2+)-sensors synaptotagmin-1 and Doc2b deform synaptic membranes during synaptic vesicle exocytosis. We discuss how local curvature generated by these and other proteins may stimulate membrane fusion and discuss the potential implications of these findings for other cellular fusion events.

文献信息

期刊

Cell

期刊简称

Cell

ISSN

0092-8674

DOI

10.1016/j.cell.2010.02.017

发表日期

2010-03-30

收录日期

2010-03-09

更新日期

2016-11-22

语言

英语

国家/地区

United States

NLM ID

0413066

外部链接

PubMed 原文 DOI: 10.1016/j.cell.2010.02.017 查看期刊详情

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Membrane curvature in synaptic vesicle fusion and beyond.

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