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PMID: 20352586 Published · ppublish English Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review

Migraine-associated vertigo: diagnosis and treatment.

Seminars in neurology ·Vol. 30 ·No. 2 ·2010-04-00 ·Pages 167-74

Cha YH

Abstract

Migraine-associated vertigo has become a well-recognized disease entity diagnosed based on a clinical history of recurrent vertigo attacks unexplained by other central or peripheral otologic abnormalities, which occurs in the patient with a history of migraine headaches. There is no international agreement on what spectrum of symptoms should be covered under this diagnosis, or what terminology should be used. The headaches and vestibular symptoms of migraine-associated vertigo may not be temporally associated, which often obscures the association. Diagnostic tests usually show nonspecific abnormalities that are also seen in patients with migraine who do not experience vestibular symptoms. Management generally follows the recommended treatment of migraine headaches, and includes dietary and lifestyle modifications and medical treatment with beta blockers, calcium channel blockers, and tricyclic amines. Small case series show that acetazolamide and lamotrigine appear to be more effective for the vertigo attacks than headaches. Vestibular rehabilitation has also been shown to be helpful in several studies. In this review, the epidemiologic and clinical features of the disorder, as well as the current state of knowledge on pathophysiology, diagnostic testing, and treatment are described.

MeSH Terms
Adrenergic beta-Antagonists/therapeutic use Anticonvulsants/therapeutic use Antidepressive Agents, Tricyclic/therapeutic use Brain/drug effects,physiopathology Calcium Channel Blockers/therapeutic use Humans Migraine Disorders/complications,physiopathology Neuropharmacology/methods Vertigo/diagnosis,drug therapy,physiopathology Vestibule, Labyrinth/drug effects,physiopathology
Chemicals
Adrenergic beta-Antagonists Anticonvulsants Antidepressive Agents, Tricyclic Calcium Channel Blockers
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Cha Yoon-Hee
Department of Neurology, University of California Los Angeles, Los Angeles, California, USA. [email protected]
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Article Info
Journal
Seminars in neurology
Abbr.
Semin Neurol
ISSN
1098-9021
Published
2010-04-00
Epub
2010-00-29
Pages
167-74
Language
English
Region
United States
NLM ID
8111343
PMCID
PMC5682200
Subset
IM
Grants
NIDCD NIH HHS · R03 DC010451 · United States
NCRR NIH HHS · U54 RR019482 · United States
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