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PMID: 2062117 Published · ppublish English Journal Article

The "staircase test": a measure of independent forelimb reaching and grasping abilities in rats.

Journal of neuroscience methods ·Vol. 36 ·No. 2-3 ·1991-02-00 ·Pages 219-28

Montoya CP, Campbell-Hope LJ, Pemberton KD, Dunnett SB

Abstract

A novel reaching test for the rat has been developed to assess the independent use of forelimbs in skilled reaching and grasping tasks. The apparatus is a plexiglas box with a removable baited double staircase. Food pellets are placed on the staircase and presented bilaterally at 7 graded stages of reaching difficulty to provide objective measures of side bias, maximum forelimb extension and grasping skill. In the present experiment, the apparatus was used to assess the reaching performance of rats following unilateral lesions of the sensorimotor cortex, unilateral lesions of the posterior cortex or bilateral lesions of the olfactory bulbs. The task has the advantage of objective over rating measurement, and the simplicity of the apparatus permits many animals to be tested concurrently.

MeSH Terms
Animals Behavior, Animal/physiology Conditioning, Operant/physiology Female Forelimb/physiology Motor Cortex/anatomy & histology,physiology Olfactory Bulb/anatomy & histology,physiology Rats Rats, Inbred Strains Visual Cortex/anatomy & histology,physiology
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Montoya C P
Department of Experimental Psychology, University of Cambridge, U.K.
Campbell-Hope L J
Pemberton K D
Dunnett S B
Article Info
Journal
Journal of neuroscience methods
Abbr.
J Neurosci Methods
ISSN
0165-0270
Published
1991-02-00
Pages
219-28
Language
English
Region
Netherlands
NLM ID
7905558
Subset
IM
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