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PMID: 20622832 Published · ppublish English Journal Article

The pros and cons of peptide-centric proteomics.

Nature biotechnology ·Vol. 28 ·No. 7 ·2010-07-00 ·Pages 659-64

Duncan MW, Aebersold R, Caprioli RM

Abstract

暂无摘要

MeSH Terms
Chromatography, Liquid Mass Spectrometry/methods Peptides/chemistry Proteomics
Chemicals
Peptides
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Duncan Mark W
Division of Endocrinology, Metabolism and Diabetes School of Medicine, University of Colorado Denver, Aurora, Colorado, USA.
Aebersold Ruedi
Caprioli Richard M
References (24)
24 references, click to expand
  1. Comparative evaluation of mass spectrometry platforms used in large-scale proteomics investigations.
    Nat Methods. 2005 Sep;2(9):667-75 PMID: 16118637
  2. Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry.
    Nat Methods. 2007 Mar;4(3):207-14 PMID: 17327847
  3. Post-translational modification of proteins.
    Adv Enzymol Relat Areas Mol Biol. 1993;67:265-98 PMID: 8322616
  4. Directed mass spectrometry: towards hypothesis-driven proteomics.
    Curr Opin Chem Biol. 2009 Dec;13(5-6):510-7 PMID: 19775930
  5. Investigating diversity in human plasma proteins.
    Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):10852-7 PMID: 16043703
  6. Proteome-wide identification of proteins and their modifications with decreased ambiguities and improved false discovery rates using unique sequence tags.
    Anal Chem. 2008 Mar 15;80(6):1871-82 PMID: 18271604
  7. Organellar proteomics: turning inventories into insights.
    EMBO Rep. 2006 Sep;7(9):874-9 PMID: 16953200
  8. A high-quality catalog of the Drosophila melanogaster proteome.
    Nat Biotechnol. 2007 May;25(5):576-83 PMID: 17450130
  9. The need for guidelines in publication of peptide and protein identification data: Working Group on Publication Guidelines for Peptide and Protein Identification Data.
    Mol Cell Proteomics. 2004 Jun;3(6):531-3 PMID: 15075378
  10. Quantitative profiling of proteins in complex mixtures using liquid chromatography and mass spectrometry.
    J Proteome Res. 2002 Jul-Aug;1(4):317-23 PMID: 12645887
  11. Guidelines for the next 10 years of proteomics.
    Proteomics. 2006 Jan;6(1):4-8 PMID: 16400714
  12. Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search.
    Anal Chem. 2002 Oct 15;74(20):5383-92 PMID: 12403597
  13. Quantifying proteins by mass spectrometry: the selectivity of SRM is only part of the problem.
    Proteomics. 2009 Mar;9(5):1124-7 PMID: 19253279
  14. Identification of nearest-neighbor peptides in protease digests by mass spectrometry for construction of sequence-ordered tryptic maps.
    Biol Mass Spectrom. 1991 Apr;20(4):210-4 PMID: 2054394
  15. Valid data from large-scale proteomics studies.
    Nat Methods. 2005 Sep;2(9):647-8 PMID: 16118632
  16. The APEX Quantitative Proteomics Tool: generating protein quantitation estimates from LC-MS/MS proteomics results.
    BMC Bioinformatics. 2008 Dec 09;9:529 PMID: 19068132
  17. Identification and relative quantitation of protein mixtures by enzymatic digestion followed by capillary reversed-phase liquid chromatography-tandem mass spectrometry.
    Anal Chem. 2002 Sep 15;74(18):4741-9 PMID: 12349978
  18. The implications of proteolytic background for shotgun proteomics.
    Mol Cell Proteomics. 2007 Sep;6(9):1589-98 PMID: 17533221
  19. Interpretation of shotgun proteomic data: the protein inference problem.
    Mol Cell Proteomics. 2005 Oct;4(10):1419-40 PMID: 16009968
  20. Science, marketing and wishful thinking in quantitative proteomics.
    Proteomics. 2008 Nov;8(22):4618-23 PMID: 18937255
  21. A model for random sampling and estimation of relative protein abundance in shotgun proteomics.
    Anal Chem. 2004 Jul 15;76(14):4193-201 PMID: 15253663
  22. High-throughput generation of selected reaction-monitoring assays for proteins and proteomes.
    Nat Methods. 2010 Jan;7(1):43-6 PMID: 19966807
  23. Quantitation in mass-spectrometry-based proteomics.
    Annu Rev Plant Biol. 2010;61:491-516 PMID: 20192741
  24. A database of mass spectrometric assays for the yeast proteome.
    Nat Methods. 2008 Nov;5(11):913-4 PMID: 18974732
Article Info
Journal
Nature biotechnology
Abbr.
Nat Biotechnol
ISSN
1546-1696
DOI
10.1038/nbt0710-659
Published
2010-07-00
Pages
659-64
Language
English
Region
United States
NLM ID
9604648
Subset
IM
External Links
PubMed source DOI: 10.1038/nbt0710-659 View journal details
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