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PMID: 20679023 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

CFD modeling of an ultrasonic separator for the removal of lipid particles from pericardial suction blood.

IEEE transactions on bio-medical engineering ·Vol. 58 ·No. 2 ·2011-02-00 ·页码 282-90

Trippa G, Ventikos Y, Taggart DP, Coussios CC

Abstract

A computational fluid dynamics (CFD) model is presented to simulate the removal of lipid particles from blood using a novel ultrasonic quarter-wavelength separator. The Lagrangian-Eulerian CFD model accounts for conservation of mass and momentum, for the presence of lipid particles of a range of diameters, for the acoustic force as experienced by the particles in the blood, as well as for gravity and other particle-fluid interaction forces. In the separator, the liquid flows radially inward within a fluid chamber formed between a disc-shaped transducer and a disc-shaped reflector. Following separation of the lipid particles, blood exits the separator axially through a central opening on the disc-shaped reflector. Separator diameters studied varied between 12 and 18 cm, and gap sizes between the discs of 600 μm, 800 μm and 1 mm were considered. Results show a strong effect of residence time of the particles within the chamber on the separation performance. Different separator configurations were identified, which could give a lipid removal performance of 95% or higher when processing 62.5 cm (3)/min of blood. The developed model provides a design method for the selection of geometric and operating parameters for the ultrasonic separator.

MeSH 主题词
Blood Component Removal/methods Blood Transfusion, Autologous Cardiac Surgical Procedures Computer Simulation Hemorheology/physiology Humans Lipids/blood,isolation & purification Models, Cardiovascular Pericardium Transducers Ultrasonics/methods
化学物质
Lipids
作者与单位
共 4 位作者,点击展开单位 / ORCID
Trippa Giuliana
Department of Engineering Science, Institute ofBiomedical Engineering, University of Oxford, Oxford, UK. [email protected]
Ventikos Yiannis
Taggart David P
Coussios Constantin-C
Article Info
Journal
IEEE transactions on bio-medical engineering
Abbr.
IEEE Trans Biomed Eng
ISSN
1558-2531
Corresponding email
Published
2011-02-00
电子出版
2010-00-29
页码
282-90
Language
English
Country/Region
United States
NLM ID
0012737
基金资助
British Heart Foundation · PG/07/010/22307 · United Kingdom
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