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PMID: 20855501 Published · ppublish English Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review

The cell biology of vision.

The Journal of cell biology ·Vol. 190 ·No. 6 ·2010-09-20 ·Pages 953-63

Sung CH, Chuang JZ

Abstract

Humans possess the remarkable ability to perceive color, shape, and motion, and to differentiate between light intensities varied by over nine orders of magnitude. Phototransduction--the process in which absorbed photons are converted into electrical responses--is the first stage of visual processing, and occurs in the outer segment, the light-sensing organelle of the photoreceptor cell. Studies of genes linked to human inherited blindness have been crucial to understanding the biogenesis of the outer segment and membrane-trafficking of photoreceptors.

MeSH Terms
Animals Cellular Senescence Eye/cytology Humans Morphogenesis Retinal Rod Photoreceptor Cells/cytology,ultrastructure Rhodopsin/metabolism Vision, Ocular/physiology
Chemicals
Rhodopsin
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Sung Ching-Hwa
Dyson Vision Research Institute, Department of Ophthalmology, Weill Cornell Medical College, New York, NY 10065, USA. [email protected]
Chuang Jen-Zen
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Article Info
Journal
The Journal of cell biology
Abbr.
J Cell Biol
ISSN
1540-8140
DOI
10.1083/jcb.201006020
Email
[email protected]
Published
2010-09-20
Pages
953-63
Language
English
Region
United States
NLM ID
0375356
PMCID
PMC3101587
Subset
IM
Grants
NEI NIH HHS · EY11307 · United States
NEI NIH HHS · R24 EY015656 · United States
NEI NIH HHS · R01 EY011307 · United States
NEI NIH HHS · EY015656 · United States
NEI NIH HHS · EY016805 · United States
NEI NIH HHS · R01 EY016805 · United States
External Links
PubMed source DOI: 10.1083/jcb.201006020 PMC Full Text View journal details
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