Intergenic suppression of spoO phenotypes by the Bacillus subtilis mutation rvtA.

Molecular & general genetics : MGG ·Vol. 194 ·No. 1-2 ·1984-00-00 ·Pages 260-4

Sharrock RA, Rubinstein S, Chan M, Leighton T

Abstract

A collection of intergenic suppressors of the Bacillus subtilis spoOF221 mutation has been isolated. One of these suppressors, rvtA, has been mapped between lys-1and aroD. The rvtA suppressor restores spoOF sporulation to wild type levels and substantially improves the sporulation efficiencies of spoOB and spoOE strains. The rvtA gene does not affect the Spo phenotype of spoOH, spoOJ or spoOK mutants. The rvtA gene also prevents the induction by aliphatic alcohols of SpoO phenocopies in wild type B. subtilis cells.

MeSH Terms

Bacillus subtilis/genetics,metabolism Bacterial Proteins/genetics,metabolism Chromosome Mapping DNA, Bacterial/genetics DNA, Intergenic/genetics Mutation/genetics Phenotype Spores, Bacterial/growth & development Suppression, Genetic/genetics

Chemicals

Bacterial Proteins DNA, Bacterial DNA, Intergenic

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Sharrock R A

Department of Microbiology and Immunology, University of California, Berkeley, California 94720, USA

Rubinstein S

Chan M

Leighton T

References (12)

12 references, click to expand

The program of protein synthesis during sporulation in Bacillus subtilis.
Cell. 1976 May;8(1):103-14 PMID: 821617
Physiological suppression of the temperature-sensitive sporulation defect in a Bacillus subtilis RNA polymerase mutant.
Mol Gen Genet. 1981;183(3):544-9 PMID: 6801429
Genetic aspects of bacterial endospore formation.
Bacteriol Rev. 1976 Dec;40(4):908-62 PMID: 12736
Alcohol-resistant sporulation mutants of Bacillus subtilis.
J Bacteriol. 1982 May;150(2):944-55 PMID: 6802803
Intergenic suppressors of temperature-sensitive sporulation in Bacillus subtilis are allele non-specific.
Mol Gen Genet. 1981;183(3):532-7 PMID: 6801427
Physiological suppression of Bacillus subtilis conditioned sporulation phenotypes: RNA polymerase and ribosomal mutations.
Mol Gen Genet. 1981;183(3):550-2 PMID: 6801430
Macrolide and aminoglycoside antibiotic resistance mutations in the bacillus subtilis ribosome resulting in temperature-sensitive sporulation.
Mol Gen Genet. 1981;183(3):538-43 PMID: 6801428
Deoxyribonucleic acid-binding proteins in vegetative Bacillus subtilis: alterations caused by stage O sporulation mutations.
J Bacteriol. 1975 Nov;124(2):977-84 PMID: 810485
Early events during bacterial endospore formation.
Adv Microb Physiol. 1979;20:103-62, 321-3 PMID: 43666
The Bacillus subtilis chromosome.
Microbiol Rev. 1980 Mar;44(1):57-82 PMID: 6774224
Developmental and genetic regulation of Bacillus subtilis genes transcribed by sigma 28-RNA polymerase.
Cell. 1983 Nov;35(1):285-93 PMID: 6313226
Pleiotropic effects of suppressor mutations in Bacillus subtilis.
J Bacteriol. 1974 Sep;119(3):961-75 PMID: 4212248

Article Info

Journal

Molecular & general genetics : MGG

Abbr.

Mol Gen Genet

ISSN

0026-8925

DOI

10.1007/BF00383525

Published

1984-00-00

Pages

260-4

Language

English

Region

Germany

NLM ID

0125036

Subset

External Links

PubMed source DOI: 10.1007/BF00383525

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Intergenic suppression of spoO phenotypes by the Bacillus subtilis mutation rvtA.

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