A sample of 2143 individuals belonging to six natural geographic regions from Mallorca (Balearic Is. Spain, 39.5N, 3.0E) was studied for the red cell enzyme polymorphisms: Esterase-D (ESD), acid phospatase-1 (ACP1), glyoxalase-I (GLO1), phosphogluconate dehydrogenase (PGD), phosphoglucomutase-1 (PGM1) and adenylate-kinase (AK1). The following gene frequencies were obtained: ESD*2'3 = 0.142, ACP1*A = 0.248, ACP1*C = 0.027, GLO1*2 = 0.529, PGD*C = 0.010, PGM1*2 = 0.221 and AK1*2 = 0.033. Most of these gene frequencies were in Hardy-Weinberg equilibrium. The subpopulation of "La Muntanya" showed significant differences for some allozymes respect to the others, in accordance with its geographic peculiarity.
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