Development of early nuclear antigen in cytomegalovirus infected cells in the presence of RNA and protein synthesis inhibitors.

The Journal of general virology ·Vol. 40 ·No. 2 ·1978-08-00 ·Pages 475-80

Reynolds DW

Abstract

Human cytomegaloviruses (HCMV) induce nuclear antigens as early as I h after infection as detected by immunofluorescence. Early antigen development occurs in the presence of DNA, RNA, and protein synthesis inhibitors and is dependent on intact viral DNA in the inoculum.

MeSH Terms

Antigens, Viral Cell Nucleus/immunology Culture Techniques Cycloheximide/pharmacology Cytarabine/pharmacology Cytomegalovirus/growth & development,immunology Dactinomycin/pharmacology Fluorescent Antibody Technique Humans Puromycin/pharmacology

Chemicals

Antigens, Viral Cytarabine Dactinomycin Puromycin Cycloheximide

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Reynolds D W

Article Info

Journal

The Journal of general virology

Abbr.

J Gen Virol

ISSN

0022-1317

DOI

10.1099/0022-1317-40-2-475

Published

1978-08-00

Pages

475-80

Language

English

Region

England

NLM ID

0077340

Subset

External Links

PubMed source DOI: 10.1099/0022-1317-40-2-475 View journal details

Analysis Services

Development of early nuclear antigen in cytomegalovirus infected cells in the presence of RNA and protein synthesis inhibitors.

Contact

WeChat Official Account