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PMID: 21177655 Published · ppublish English Introductory Journal Article Research Support, N.I.H., Intramural Research Support, Non-U.S. Gov't

The 2011 Nucleic Acids Research Database Issue and the online Molecular Biology Database Collection.

Nucleic acids research ·Vol. 39 ·No. Database issue ·2011-01-00 ·Pages D1-6

Galperin MY, Cochrane GR

Abstract

The current 18th Database Issue of Nucleic Acids Research features descriptions of 96 new and 83 updated online databases covering various areas of molecular biology. It includes two editorials, one that discusses COMBREX, a new exciting project aimed at figuring out the functions of the 'conserved hypothetical' proteins, and one concerning BioDBcore, a proposed description of the 'minimal information about a biological database'. Papers from the members of the International Nucleotide Sequence Database collaboration (INSDC) describe each of the participating databases, DDBJ, ENA and GenBank, principles of data exchange within the collaboration, and the recently established Sequence Read Archive. A testament to the longevity of databases, this issue includes updates on the RNA modification database, Definition of Secondary Structure of Proteins (DSSP) and Homology-derived Secondary Structure of Proteins (HSSP) databases, which have not been featured here in >12 years. There is also a block of papers describing recent progress in protein structure databases, such as Protein DataBank (PDB), PDB in Europe (PDBe), CATH, SUPERFAMILY and others, as well as databases on protein structure modeling, protein-protein interactions and the organization of inter-protein contact sites. Other highlights include updates of the popular gene expression databases, GEO and ArrayExpress, several cancer gene databases and a detailed description of the UK PubMed Central project. The Nucleic Acids Research online Database Collection, available at: http://www.oxfordjournals.org/nar/database/a/, now lists 1330 carefully selected molecular biology databases. The full content of the Database Issue is freely available online at the Nucleic Acids Research web site (http://nar.oxfordjournals.org/).

MeSH Terms
Databases, Nucleic Acid Databases, Protein Internet Molecular Biology
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Galperin Michael Y
National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA. [email protected]
Cochrane Guy R
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
1362-4962
DOI
10.1093/nar/gkq1243
Email
[email protected]
Published
2011-01-00
Pages
D1-6
Language
English
Region
England
NLM ID
0411011
PMCID
PMC3013748
Subset
IM
Grants
Intramural NIH HHS · Z99 LM999999 · United States
External Links
PubMed source DOI: 10.1093/nar/gkq1243 PMC Full Text View journal details
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