Cell cycle control in eukaryotes: molecular mechanisms of cdc2 activation.

Trends in biochemical sciences ·Vol. 15 ·No. 10 ·1990-10-00 ·Pages 378-83

Draetta G

Abstract

cdc2 kinase regulates the progression of eukaryotic cells through the division cycle. Events such as cell growth, DNA replication and mitosis are coordinated through the activation of specific forms of this kinase. Here I discuss our present knowledge of the mechanisms that regulate the activity of cdc2 kinase.

Related Genes

CDC28 cdc2

MeSH Terms

Amino Acid Sequence Animals Cell Cycle/genetics Cyclins/genetics Genes, Fungal Humans Molecular Sequence Data Protein Kinases/genetics Yeasts/genetics

Chemicals

Cyclins Protein Kinases

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Draetta G

Differentiation Programme, European Molecular Biology Laboratory, Heidelberg, FRG.

Article Info

Journal

Trends in biochemical sciences

Abbr.

Trends Biochem Sci

ISSN

0968-0004

DOI

10.1016/0968-0004(90)90235-4

Published

1990-10-00

Pages

378-83

Language

English

Region

England

NLM ID

7610674

Subset

External Links

PubMed source DOI: 10.1016/0968-0004(90)90235-4 View journal details

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Cell cycle control in eukaryotes: molecular mechanisms of cdc2 activation.

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