Genetic mapping of a cloned sequence responsible for susceptibility to ecotropic murine leukemia viruses.
A mouse cDNA that confers susceptibility to ecotropic murine leukemia viruses following transfection into human EJ cells has been cloned and sequenced. We show that this sequence is likely to be Rec-1, the chromosome 5 locus originally defined by studies with somatic cell hybrids as responsible for virus susceptibility, and provide a specific chromosomal map position for this locus by analysis of an interspecies backcross. This locus maps in the distal region of chromosome 5 and is thus not within the cluster of retrovirus-related genes near the centromere.
16 references, click to expand
-
Genetic analysis of endogenous xenotropic murine leukemia viruses: association with two common mouse mutations and the viral restriction locus Fv-1.J Virol. 1989 Apr;63(4):1763-74 PMID: 2564439
-
Susceptibility of wild mouse cells to exogenous infection with xenotropic leukemia viruses: control by a single dominant locus on chromosome 1.J Virol. 1985 Sep;55(3):690-5 PMID: 2991590
-
Maps of linkage and synteny homologies between mouse and man.Trends Genet. 1989 Mar;5(3):82-6 PMID: 2660365
-
Genetic identification of endogenous polytropic proviruses by using recombinant inbred mice.J Virol. 1989 Sep;63(9):3810-21 PMID: 2547997
-
Membrane receptors for murine leukemia viruses: characterization using the purified viral envelope glycoprotein, gp71.Cell. 1976 Jul;8(3):365-71 PMID: 8213
-
Identification of mouse chromosomes required for murine leukemia virus replication.Cell. 1977 Aug;11(4):949-56 PMID: 196770
-
Mouse chromosome 5 codes for ecotropic murine leukaemia virus cell-surface receptor.Nature. 1978 Jul 6;274(5666):60-2 PMID: 566388
-
Assignment of the receptor for ecotropic murine leukemia virus to mouse chromosome 5.J Exp Med. 1978 Aug 1;148(2):451-65 PMID: 212501
-
Genetic mapping of the ecotropic murine leukemia virus-inducing locus of BALB/c mouse to chromosome 5.Science. 1979 Apr 6;204(4388):69-71 PMID: 219475
-
Genetic linkage of C3H/HeJ and BALB/c endogenous ecotropic C-type viruses to phosphoglucomutase-1 on chromosome 5.Science. 1979 Apr 6;204(4388):71-3 PMID: 219476
-
Cell surface receptors for endogenous mouse type C viral glycoproteins and epidermal growth factor: tissue distribution in vivo and possible participation in specific cell-cell interaction.J Supramol Struct. 1980;14(3):343-52 PMID: 6261043
-
Interference grouping of murine leukemia viruses: a distinct receptor for the MCF-recombinant viruses in mouse cells.Virology. 1982 Jul 15;120(1):251-7 PMID: 6285602
-
A mouse gene on chromosome 5 that restricts infectivity of mink cell focus-forming recombinant murine leukemia viruses.J Exp Med. 1983 Jul 1;158(1):16-24 PMID: 6306133
-
Genetic mapping of a mouse chromosomal locus required for mink cell focus-forming virus replication.J Virol. 1983 Oct;48(1):300-3 PMID: 6310150
-
Different recombinant murine leukemia viruses use different cell surface receptors.Virology. 1984 Jul 15;136(1):144-52 PMID: 6330990
-
A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection.Cell. 1989 May 19;57(4):659-66 PMID: 2541919
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