rBioNet: A COBRA toolbox extension for reconstructing high-quality biochemical networks.

Genome-scale metabolic networks are widely used in systems biology. However, to date no freely available tool exists that ensures quality control during the reconstruction process. Here, we present a COBRA toolbox extension, rBioNet, enabling the construction of publication-level biochemical networks while enforcing necessary quality control measures. rBioNet has an intuitive user interface facilitating the reconstruction process for novices and experts. The rBioNet is freely available from http://opencobra.sourceforge.net.