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PMID: 21665999 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Botrytis cinerea manipulates the antagonistic effects between immune pathways to promote disease development in tomato.

The Plant cell ·Vol. 23 ·No. 6 ·2011-06-00 ·Pages 2405-21

El Oirdi M, El Rahman TA, Rigano L, El Hadrami A, Rodriguez MC, Daayf F, Vojnov A, Bouarab K

Abstract

Plants have evolved sophisticated mechanisms to sense and respond to pathogen attacks. Resistance against necrotrophic pathogens generally requires the activation of the jasmonic acid (JA) signaling pathway, whereas the salicylic acid (SA) signaling pathway is mainly activated against biotrophic pathogens. SA can antagonize JA signaling and vice versa. Here, we report that the necrotrophic pathogen Botrytis cinerea exploits this antagonism as a strategy to cause disease development. We show that B. cinerea produces an exopolysaccharide, which acts as an elicitor of the SA pathway. In turn, the SA pathway antagonizes the JA signaling pathway, thereby allowing the fungus to develop its disease in tomato (Solanum lycopersicum). SA-promoted disease development occurs through Nonexpressed Pathogen Related1. We also show that the JA signaling pathway required for tomato resistance against B. cinerea is mediated by the systemin elicitor. These data highlight a new strategy used by B. cinerea to overcome the plant's defense system and to spread within the host.

MeSH Terms
Anti-Infective Agents Botrytis/metabolism,pathogenicity Carbohydrate Conformation Cyclopentanes/metabolism Defensins/genetics,metabolism Glucans/chemistry,metabolism Immunity, Innate/immunology Lycopersicon esculentum/genetics,immunology,microbiology Molecular Sequence Data Oxylipins/metabolism Plant Diseases/immunology,microbiology Plant Leaves/immunology,microbiology Plant Proteins/genetics,metabolism Plants, Genetically Modified Salicylic Acid/metabolism Signal Transduction/immunology
Chemicals
Anti-Infective Agents Cyclopentanes Defensins Glucans Oxylipins Plant Proteins jasmonic acid Salicylic Acid
Authors & Affiliations
8 authors, click to expand affiliations / ORCID
El Oirdi Mohamed
Centre de Recherche en Amélioration Végétale, Département de Biologie, Faculté des Sciences, Université de Sherbrooke, Sherbrooke, Quebec J1K 2R1, Canada.
El Rahman Taha Abd
Rigano Luciano
El Hadrami Abdelbasset
Rodriguez María Cecilia
Daayf Fouad
Vojnov Adrian
Bouarab Kamal
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Article Info
Journal
The Plant cell
Abbr.
Plant Cell
ISSN
1532-298X
DOI
10.1105/tpc.111.083394
Published
2011-06-00
Epub
2011-00-10
Pages
2405-21
Language
English
Region
England
NLM ID
9208688
PMCID
PMC3160041
Subset
IM
External Links
PubMed source DOI: 10.1105/tpc.111.083394 PMC Full Text View journal details
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