The antifungal antibiotic sinefungin as a very active inhibitor of methyltransferases and of the transformation of chick embryo fibroblasts by Rous sarcoma virus.

Biochemical and biophysical research communications ·Vol. 85 ·No. 1 ·1978-11-14 ·Pages 371-6

Vedel M, Lawrence F, Robert-Gero M, Lederer E

Abstract

暂无摘要

MeSH Terms

Adenosine/analogs & derivatives,pharmacology Animals Antifungal Agents/pharmacology Avian Sarcoma Viruses Cell Line Cell Transformation, Viral/drug effects Chick Embryo Fibroblasts/metabolism Kinetics Methyltransferases/antagonists & inhibitors S-Adenosylhomocysteine/pharmacology S-Adenosylmethionine/pharmacology Structure-Activity Relationship

Chemicals

Antifungal Agents S-Adenosylmethionine S-Adenosylhomocysteine Methyltransferases Adenosine

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Vedel M

Lawrence F

Robert-Gero M

Lederer E

Article Info

Journal

Biochemical and biophysical research communications

Abbr.

Biochem Biophys Res Commun

ISSN

0006-291X

DOI

10.1016/s0006-291x(78)80052-7

Published

1978-11-14

Pages

371-6

Language

English

Region

United States

NLM ID

0372516

Subset

External Links

PubMed source DOI: 10.1016/s0006-291x(78)80052-7 View journal details

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The antifungal antibiotic sinefungin as a very active inhibitor of methyltransferases and of the transformation of chick embryo fibroblasts by Rous sarcoma virus.

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