Rad18 emerges as a critical regulator of the Fanconi anemia pathway.

Cell cycle (Georgetown, Tex.) ·Vol. 10 ·No. 15 ·2011-08-01 ·Pages 2414-5

Keaton MA, Dutta A

Abstract

暂无摘要

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Keaton Mignon A

Dutta Anindya

References (7)

7 references, click to expand

Expanded roles of the Fanconi anemia pathway in preserving genomic stability.
Genes Dev. 2010 Aug 15;24(16):1680-94 PMID: 20713514
A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway.
Mol Cell. 2007 Dec 14;28(5):786-97 PMID: 18082604
Regulation of monoubiquitinated PCNA by DUB autocleavage.
Nat Cell Biol. 2006 Apr;8(4):339-47 PMID: 16531995
Rad18 E3 ubiquitin ligase activity mediates Fanconi anemia pathway activation and cell survival following DNA Topoisomerase 1 inhibition.
Cell Cycle. 2011 May 15;10(10):1625-38 PMID: 21478670
Rad18-mediated translesion synthesis of bulky DNA adducts is coupled to activation of the Fanconi anemia DNA repair pathway.
J Biol Chem. 2010 Oct 8;285(41):31525-36 PMID: 20675655
CRL4(Cdt2) E3 ubiquitin ligase monoubiquitinates PCNA to promote translesion DNA synthesis.
Mol Cell. 2010 Jan 15;37(1):143-9 PMID: 20129063
The E3 ubiquitin ligase RAD18 regulates ubiquitylation and chromatin loading of FANCD2 and FANCI.
Blood. 2011 May 12;117(19):5078-87 PMID: 21355096

Article Info

Journal

Cell cycle (Georgetown, Tex.)

Abbr.

Cell Cycle

ISSN

1551-4005

DOI

Published

2011-08-01

Epub

2011-00-01

Pages

2414-5

Language

English

Region

United States

NLM ID

101137841

PMCID

PMC3233489

Grants

NCI NIH HHS · R01 CA060499 · United States

NCI NIH HHS · R01 CA060499-18 · United States

Corrections

CommentOn

PMID: 21478670

External Links

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