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PMID: 219042 Published · ppublish English Journal Article

Granular cell myoblastoma: positive staining for carcinoembryonic antigen.

Journal of clinical pathology ·Vol. 32 ·No. 3 ·1979-03-00 ·Pages 219-24

Shousha S, Lyssiotis T

Abstract

An immunoperoxidase technique for the detection of carcinoembryonic antigen was applied to 10 cases of granular cell myoblastoma. Consistent, strong, intracytoplasmic granular staining, which can be easily interpreted, was obtained in all cases. Schwannomas, neurofibromas, dermatofibromas, and leiomyomas were negative. The test is helpful in confirming doubtful cases. The results tend to support the suggestion that granular cell myoblastoma is derived from perineural rather than endoneural cells.

MeSH Terms
Adult Aged Breast Neoplasms/immunology Carcinoembryonic Antigen/analysis Cytoplasmic Granules/immunology Female Humans Immunoenzyme Techniques Male Middle Aged Neoplasms, Muscle Tissue/immunology Skin Neoplasms/immunology Tongue Neoplasms/immunology
Chemicals
Carcinoembryonic Antigen
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Shousha S
Lyssiotis T
References (14)
14 references, click to expand
  1. Histogenesis of the granular-cell myoblastoma.
    J Pathol Bacteriol. 1956 Jan;71(1):85-94 PMID: 13307337
  2. Granular cell myoblastoma--a misnomer. Electron microscopic and histochemical evidence concerning its Schwann cell derivation and nature (granular cell schwannoma).
    Cancer. 1962 Sep-Oct;15:936-54 PMID: 13893237
  3. "Myoblastoma" of the neurophypophysis.
    J Pathol Bacteriol. 1962 Apr;83:455-61 PMID: 13875047
  4. The histogenesis of granular-cell myoblastoma (? granular-cell perineural fibroblastoma).
    J Pathol Bacteriol. 1950 Jul;62(3):351-62 PMID: 14784899
  5. Immunohistochemistry of carcinoembryonic antigen: characterisation of cross-reactions with other glycoproteins.
    Gut. 1977 Oct;18(10):779-85 PMID: 73495
  6. Correlation of carcinoembryonic antigen in tissue sections with spread of mammary carcinoma.
    Histopathology. 1978 Nov;2(6):433-47 PMID: 365699
  7. Carcinoembryonic antigen in histopathology: immunoperoxidase staining of conventional tissue sections.
    J Natl Cancer Inst. 1976 Jul;57(1):11-22 PMID: 794493
  8. Light- and electron-microscope study of the origin of granular-cell myoblastoma.
    J Pathol. 1973 Feb;109(2):101-11 PMID: 4124410
  9. Myogenous origin of a granular cell tumor of the urinary bladder.
    Am J Clin Pathol. 1971 Dec;56(6):736-49 PMID: 4108241
  10. Light- and electron-microscope studies on the granular cell myoblastoma of the tongue.
    J Pathol. 1969 Feb;97(2):339-55 PMID: 4311005
  11. Granular cell myoblastoma.
    Cancer. 1970 Mar;25(3):542-50 PMID: 4313651
  12. Cancer, differentiation and embryonic antigens: some central problems.
    Adv Cancer Res. 1974;19(0):105-65 PMID: 4604182
  13. Carcinoembryonic antigen: isolation of a sub-fraction with high specific activity.
    Br J Cancer. 1976 Apr;33(4):357-62 PMID: 1268028
  14. Demonstration of an antigen common to several varieties of neoplasia.
    N Engl J Med. 1971 Jul 15;285(3):138-41 PMID: 5104234
Article Info
Journal
Journal of clinical pathology
Abbr.
J Clin Pathol
ISSN
0021-9746
DOI
10.1136/jcp.32.3.219
Published
1979-03-00
Pages
219-24
Language
English
Region
England
NLM ID
0376601
PMCID
PMC1145625
Subset
IM
External Links
PubMed source DOI: 10.1136/jcp.32.3.219 PMC Full Text View journal details
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