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PMID: 21956324 Published · epublish English Journal Article Comment

Immunology: recognition of a unique partner.

Nature ·Vol. 477 ·No. 7366 ·2011-09-28 ·Pages 543-4

Monack DM

Abstract

暂无摘要

MeSH Terms
Animals Antigens, Bacterial/immunology Apoptosis Regulatory Proteins/immunology,metabolism Bacteria/immunology Bacterial Secretion Systems/immunology CARD Signaling Adaptor Proteins/immunology,metabolism Calcium-Binding Proteins/immunology,metabolism Flagellin/immunology Humans Immunity, Innate/immunology Inflammasomes/immunology Neuronal Apoptosis-Inhibitory Protein/immunology
Chemicals
Antigens, Bacterial Apoptosis Regulatory Proteins Bacterial Secretion Systems CARD Signaling Adaptor Proteins Calcium-Binding Proteins Inflammasomes Ipaf protein, mouse NLRC4 protein, human Neuronal Apoptosis-Inhibitory Protein Flagellin
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Monack Denise M
Department of Microbiology and Immunology, Stanford School of Medicine, Stanford University, Stanford, California 94305, USA. [email protected]
References (5)
5 references, click to expand
  1. Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin.
    Nat Immunol. 2008 Oct;9(10):1171-8 PMID: 18724372
  2. The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus.
    Nature. 2011 Sep 14;477(7366):596-600 PMID: 21918512
  3. The inflammasomes: guardians of the body.
    Annu Rev Immunol. 2009;27:229-65 PMID: 19302040
  4. Molecular mechanisms of inflammasome activation during microbial infections.
    Immunol Rev. 2011 Sep;243(1):174-90 PMID: 21884176
  5. Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity.
    Nature. 2011 Aug 28;477(7366):592-5 PMID: 21874021
Article Info
Journal
Nature
Abbr.
Nature
ISSN
1476-4687
DOI
10.1038/477543a
Email
[email protected]
Published
2011-09-28
Epub
2011-00-28
Pages
543-4
Language
English
Region
England
NLM ID
0410462
Subset
IM
Corrections
CommentOn
PMID: 21874021
CommentOn
PMID: 21918512
External Links
PubMed source DOI: 10.1038/477543a View journal details
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