Microgranular variant of acute promyelocytic leukemia with normal conventional cytogenetics, negative PML/RARA FISH and positive PML/RARA transcripts by RT-PCR.

Adult Chromosomes, Human, Pair 15 Chromosomes, Human, Pair 17 Cytogenetic Analysis Humans In Situ Hybridization, Fluorescence Leukemia, Promyelocytic, Acute/genetics,pathology Male Nuclear Proteins/genetics Promyelocytic Leukemia Protein RNA, Messenger Receptors, Retinoic Acid/genetics Retinoic Acid Receptor alpha Reverse Transcriptase Polymerase Chain Reaction Transcription Factors/genetics Translocation, Genetic Tumor Suppressor Proteins/genetics

Nuclear Proteins Promyelocytic Leukemia Protein RARA protein, human RNA, Messenger Receptors, Retinoic Acid Retinoic Acid Receptor alpha Transcription Factors Tumor Suppressor Proteins PML protein, human