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PMID: 22049 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Neurotransmitter synthesis and uptake by isolated sympathetic neurones in microcultures.

Nature ·Vol. 270 ·No. 5633 ·1977-11-10 ·Pages 147-51

Reichardt LF, Patterson PH

Abstract

Assays of isolated single sympathetic neurones show that their transmitter functions can be either adrenergic or cholinergic depending on growth conditions. The data suggest that the number of transmitters made by most mature individual neurones is restricted.

MeSH Terms
Acetylcholine/biosynthesis Cell Differentiation Cells, Cultured Neurons/metabolism Neurotransmitter Agents/metabolism Norepinephrine/biosynthesis,metabolism Sympathetic Nervous System/cytology,metabolism Synapses/metabolism
Chemicals
Neurotransmitter Agents Acetylcholine Norepinephrine
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Reichardt L F
Patterson P H
Article Info
Journal
Nature
Abbr.
Nature
ISSN
0028-0836
DOI
10.1038/270147a0
Published
1977-11-10
Pages
147-51
Language
English
Region
England
NLM ID
0410462
Subset
IM
External Links
PubMed source DOI: 10.1038/270147a0 View journal details
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