Cysteine 38 holds the key to NF-κB activation.

Molecular cell ·第 45 卷 ·第 1 期 ·2012-03-30

Perkins Neil D

摘要

The importance of parallel signaling pathways controlling NF-κB subunit posttranslational modifications is demonstrated by Sen et al. (2012), who reveal that RelA (p65) sulfhydration, at its highly conserved cysteine 38 residue, regulates association with the coactivator RPS3, DNA binding, and antiapoptotic gene expression.

文献信息

期刊

Molecular cell

期刊简称

Mol Cell

ISSN

1097-2765

DOI

10.1016/j.molcel.2011.12.023

发表日期

2012-03-30

收录日期

2012-01-16

更新日期

2012-01-16

语言

英语

国家/地区

United States

NLM ID

9802571

外部链接

PubMed 原文 DOI: 10.1016/j.molcel.2011.12.023 查看期刊详情

分析服务

Cysteine 38 holds the key to NF-κB activation.

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