Targeting the microbiota-gut-brain axis to modulate behavior: which bacterial strain will translate best to humans?

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 109 ·No. 4 ·2012-01-24 ·Pages E174; author reply E176

McLean PG, Bergonzelli GE, Collins SM, Bercik P

Abstract

暂无摘要

MeSH Terms

Animals Emotions/physiology Lactobacillus/physiology Male Receptors, GABA/genetics Vagus Nerve/physiology

Chemicals

Receptors, GABA

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

McLean Peter G

Bergonzelli Gabriella E

Collins Stephen M

Bercik Premysl

References (4)

4 references, click to expand

Lactobacillus reuteri enhances excitability of colonic AH neurons by inhibiting calcium-dependent potassium channel opening.
J Cell Mol Med. 2009 Aug;13(8B):2261-2270 PMID: 19210574
Chronic gastrointestinal inflammation induces anxiety-like behavior and alters central nervous system biochemistry in mice.
Gastroenterology. 2010 Dec;139(6):2102-2112.e1 PMID: 20600016
Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve.
Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):16050-5 PMID: 21876150
The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut-brain communication.
Neurogastroenterol Motil. 2011 Dec;23(12):1132-9 PMID: 21988661

Article Info

Journal

Proceedings of the National Academy of Sciences of the United States of America

Abbr.

Proc Natl Acad Sci U S A

ISSN

1091-6490

DOI

10.1073/pnas.1118626109

Published

2012-01-24

Epub

2012-00-13

Pages

E174; author reply E176

Language

English

Region

United States

NLM ID

7505876

PMCID

PMC3268323

Subset

Corrections

CommentOn

PMID: 21876150

External Links

PubMed source DOI: 10.1073/pnas.1118626109 PMC Full Text View journal details

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Targeting the microbiota-gut-brain axis to modulate behavior: which bacterial strain will translate best to humans?

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