Sequence and location of the poly C tract in aphtho- and cardiovirus RNA.

Nucleic acids research ·Vol. 6 ·No. 7 ·1979-06-11 ·Pages 2381-90

Black DN, Stephenson P, Rowlands DJ, Brown F

Abstract

The poly C tract in the RNA of the aphtho- and cardio viruses has been examined in several isolates of foot-and-mouth disease virus (FMDV) and encephalomyocarditis (EMC) virus. The length of the tract is variable, containing 100 to 170 bases in the FMDV isolates and 80 to 250 bases in the EMC virus isolates. Each poly C tract contains c. 10% A and U residues, located at the 5' end, i.e. most of the tract is a continuous run of C residues. The position of the tract on the genome was the same in each of the FMDV isolates, about 400 bases from the 5' end, whereas in the EMC virus isolates it was about 150 bases from the 5' end.

MeSH Terms

Animals Aphthovirus/analysis Base Sequence Encephalomyocarditis virus/analysis Poly C/analysis Polyribonucleotides/analysis RNA, Viral/analysis Ribonuclease T1 Ribonucleases Species Specificity

Chemicals

Polyribonucleotides RNA, Viral Poly C Ribonucleases Ribonuclease T1

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Black D N

Stephenson P

Rowlands D J

Brown F

References (12)

12 references, click to expand

PURIFICATION OF RADIOACTIVE FOOT-AND-MOUTH DISEASE VIRUS.
Nature. 1963 Sep 21;199:1168-70 PMID: 14072035
Picornaviridae: second report.
Intervirology. 1978;10(3):165-80 PMID: 210136
Identification of specific fragments containing the 5' end of poliovirus RNA after ribonuclease III digestion.
Nucleic Acids Res. 1978 Nov;5(11):4039-54 PMID: 214765
The genomic RNA of mengovirus. II: Comparative analysis of the standard and denser virions.
Virology. 1978 Apr;85(2):378-86 PMID: 208232
More precise location of the polycytidylic acid tract in foot and mouth disease virus RNA.
J Virol. 1978 May;26(2):335-43 PMID: 207892
The location of the ploy(C) tract in the RNA of foot-and-mouth disease virus.
J Gen Virol. 1976 Dec;33(3):493-501 PMID: 187724
Biochemical analysis of a virulent and an avirulent strain of foot-and-mouth disease virus.
J Gen Virol. 1977 Jan;34(1):87-105 PMID: 188983
New rapid gel sequencing method for RNA.
Nature. 1977 Oct 27;269(5631):833-6 PMID: 927512
An efficient mRNA-dependent translation system from reticulocyte lysates.
Eur J Biochem. 1976 AUG 1;67(1):247-56 PMID: 823012
Presence of a large poly(rC) tract within the RNA of encephalomyocarditis virus.
Nature. 1974 Apr 19;248(5450):675-8 PMID: 4364433
Poly(C) in animal viral RNAs.
Nature. 1974 Sep 27;251(5473):342-4 PMID: 4372534
Poly(C) sequence is located near the 5'-end of encephalomyocarditis virus RNA.
Biochem Biophys Res Commun. 1976 Jul 26;71(2):551-7 PMID: 183773

Article Info

Journal

Nucleic acids research

Abbr.

Nucleic Acids Res

ISSN

0305-1048

DOI

10.1093/nar/6.7.2381

Published

1979-06-11

Pages

2381-90

Language

English

Region

England

NLM ID

0411011

PMCID

PMC327860

Subset

External Links

PubMed source DOI: 10.1093/nar/6.7.2381 PMC Full Text View journal details

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Sequence and location of the poly C tract in aphtho- and cardiovirus RNA.

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