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PMID: 22453911 Published · ppublish English Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Protein interaction data curation: the International Molecular Exchange (IMEx) consortium.

Nature methods ·Vol. 9 ·No. 4 ·2012-04-00 ·Pages 345-50

Orchard S, Kerrien S, Abbani S, Aranda B, Bhate J, Bidwell S, Bridge A, Briganti L, Brinkman FS, Brinkman F, Cesareni G, Chatr-aryamontri A, Chautard E, Chen C, Dumousseau M, Goll J, Hancock RE, Hancock R, Hannick LI, Jurisica I, Khadake J, Lynn DJ, Mahadevan U, Perfetto L, Raghunath A, Ricard-Blum S, Roechert B, Salwinski L, Stümpflen V, Tyers M, Uetz P, Xenarios I, Hermjakob H

Abstract

The International Molecular Exchange (IMEx) consortium is an international collaboration between major public interaction data providers to share literature-curation efforts and make a nonredundant set of protein interactions available in a single search interface on a common website (http://www.imexconsortium.org/). Common curation rules have been developed, and a central registry is used to manage the selection of articles to enter into the dataset. We discuss the advantages of such a service to the user, our quality-control measures and our data-distribution practices.

MeSH Terms
Databases, Protein Periodicals as Topic Protein Binding Protein Interaction Mapping Proteins/chemistry,metabolism Quality Control
Chemicals
Proteins
Authors & Affiliations
33 authors, click to expand affiliations / ORCID
Orchard Sandra
European Molecular Biology Laboratory-European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, UK. [email protected]
Kerrien Samuel
Abbani Sara
Aranda Bruno
Bhate Jignesh
Bidwell Shelby
Bridge Alan
Briganti Leonardo
Brinkman Fiona S L
Brinkman Fiona
Cesareni Gianni
Chatr-aryamontri Andrew
Chautard Emilie
Chen Carol
Dumousseau Marine
Goll Johannes
Hancock Robert E W
Hancock Robert
Hannick Linda I
Jurisica Igor
Khadake Jyoti
Lynn David J
Mahadevan Usha
Perfetto Livia
Raghunath Arathi
Ricard-Blum Sylvie
Roechert Bernd
Salwinski Lukasz
Stümpflen Volker
Tyers Mike
Uetz Peter
Xenarios Ioannis
Hermjakob Henning
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Article Info
Journal
Nature methods
Abbr.
Nat Methods
ISSN
1548-7105
DOI
10.1038/nmeth.1931
Email
[email protected]
Published
2012-04-00
Pages
345-50
Language
English
Region
United States
NLM ID
101215604
PMCID
PMC3703241
Subset
IM
Grants
NIH HHS · R01 OD010929 · United States
NIGMS NIH HHS · R01 GM071909 · United States
CIHR · Canada
Wellcome Trust · 092076 · United Kingdom
NIGMS NIH HHS · GM071909 · United States
Corrections
ErratumIn
-
External Links
PubMed source DOI: 10.1038/nmeth.1931 PMC Full Text View journal details
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