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PMID: 22565958 Published · epublish English Letter Research Support, U.S. Gov't, Non-P.H.S.

High-efficiency TALEN-based gene editing produces disease-resistant rice.

Nature biotechnology ·Vol. 30 ·No. 5 ·2012-05-07 ·Pages 390-2

Li T, Liu B, Spalding MH, Weeks DP, Yang B

Abstract

暂无摘要

MeSH Terms
Base Sequence Biotechnology/methods DNA/genetics Genetic Techniques Models, Genetic Molecular Sequence Data Mutation Oryza/genetics Plant Diseases/microbiology Polymorphism, Genetic RNA Editing Xanthomonas/metabolism
Chemicals
DNA
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Li Ting
Liu Bo
Spalding Martin H
Weeks Donald P
Yang Bing
References (14)
14 references, click to expand
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  2. Sucrose efflux mediated by SWEET proteins as a key step for phloem transport.
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  3. Modularly assembled designer TAL effector nucleases for targeted gene knockout and gene replacement in eukaryotes.
    Nucleic Acids Res. 2011 Aug;39(14):6315-25 PMID: 21459844
  4. TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain.
    Nucleic Acids Res. 2011 Jan;39(1):359-72 PMID: 20699274
  5. Targeted gene disruption in somatic zebrafish cells using engineered TALENs.
    Nat Biotechnol. 2011 Aug 05;29(8):697-8 PMID: 21822241
  6. Os8N3 is a host disease-susceptibility gene for bacterial blight of rice.
    Proc Natl Acad Sci U S A. 2006 Jul 5;103(27):10503-10508 PMID: 16798873
  7. Genetic engineering of human pluripotent cells using TALE nucleases.
    Nat Biotechnol. 2011 Jul 07;29(8):731-4 PMID: 21738127
  8. De novo-engineered transcription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks.
    Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2623-8 PMID: 21262818
  9. Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting.
    Nucleic Acids Res. 2011 Jul;39(12):e82 PMID: 21493687
  10. Rice xa13 recessive resistance to bacterial blight is defeated by induction of the disease susceptibility gene Os-11N3.
    Plant Cell. 2010 Nov;22(11):3864-76 PMID: 21098734
  11. A TALE nuclease architecture for efficient genome editing.
    Nat Biotechnol. 2011 Feb;29(2):143-8 PMID: 21179091
  12. Targeting DNA double-strand breaks with TAL effector nucleases.
    Genetics. 2010 Oct;186(2):757-61 PMID: 20660643
  13. Knockout rats generated by embryo microinjection of TALENs.
    Nat Biotechnol. 2011 Aug 05;29(8):695-6 PMID: 21822240
  14. Targeted genome editing across species using ZFNs and TALENs.
    Science. 2011 Jul 15;333(6040):307 PMID: 21700836
Article Info
Journal
Nature biotechnology
Abbr.
Nat Biotechnol
ISSN
1546-1696
DOI
10.1038/nbt.2199
Published
2012-05-07
Epub
2012-00-07
Pages
390-2
Language
English
Region
United States
NLM ID
9604648
Subset
IM
External Links
PubMed source DOI: 10.1038/nbt.2199 View journal details
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