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PMID: 226981 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Use of the UGA terminator as a tryptophan codon in yeast mitochondria.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 76 ·No. 8 ·1979-08-00 ·Pages 3784-5

Macino G, Coruzzi G, Nobrega FG, Li M, Tzagoloff A

Abstract

We propose that the UGA terminator regularly occurs as a tryptophan codon in yeast mitochondrial DNA. This conclusion is based on the sequence analysis of mitochondrial DNA regions coding for structural genes of cytochrome b, cytochrome oxidase, and the ATPase.

MeSH Terms
Base Sequence Codon DNA, Mitochondrial/genetics Electron Transport Complex IV/genetics Genes Genetic Code Mutation Peptide Chain Termination, Translational RNA, Messenger Saccharomyces cerevisiae/genetics Tryptophan/genetics
Chemicals
Codon DNA, Mitochondrial RNA, Messenger Tryptophan Electron Transport Complex IV
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Macino G
Coruzzi G
Nobrega F G
Li M
Tzagoloff A
References (9)
9 references, click to expand
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    Proc Natl Acad Sci U S A. 1979 Apr;76(4):1663-7 PMID: 156363
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    J Biol Chem. 1971 Dec 10;246(23):7328-36 PMID: 4256832
  7. Mitochondrial genetics. IV. Allelism and mapping studies of oligomycin resistant mutants in S. cerevisiae.
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  8. Cytochrome c oxidase from bakers' yeast. III. Physical characterization of isolated subunits and chemical evidence for two different classes of polypeptides.
    J Biol Chem. 1975 Jan 25;250(2):752-61 PMID: 163233
  9. Identification of two products of mitochondrial protein synthesis associated with mitochondrial adenosine triphosphatase from Neurospora crassa.
    Eur J Biochem. 1975 May;54(1):97-106 PMID: 125201
Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.76.8.3784
Published
1979-08-00
Pages
3784-5
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC383918
Subset
IM
Databases
GENBANK
K02200
External Links
PubMed source DOI: 10.1073/pnas.76.8.3784 PMC Full Text View journal details
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