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PMID: 22720055 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Leukemia gene atlas--a public platform for integrative exploration of genome-wide molecular data.

PloS one ·Vol. 7 ·No. 6 ·2012-00-00 ·Pages e39148

Hebestreit K, Gröttrup S, Emden D, Veerkamp J, Ruckert C, Klein HU, Müller-Tidow C, Dugas M

Abstract

Leukemias are exceptionally well studied at the molecular level and a wealth of high-throughput data has been published. But further utilization of these data by researchers is severely hampered by the lack of accessible integrative tools for viewing and analysis. We developed the Leukemia Gene Atlas (LGA) as a public platform designed to support research and analysis of diverse genomic data published in the field of leukemia. With respect to leukemia research, the LGA is a unique resource with comprehensive search and browse functions. It provides extensive analysis and visualization tools for various types of molecular data. Currently, its database contains data from more than 5,800 leukemia and hematopoiesis samples generated by microarray gene expression, DNA methylation, SNP and next generation sequencing analyses. The LGA allows easy retrieval of large published data sets and thus helps to avoid redundant investigations. It is accessible at www.leukemia-gene-atlas.org.

MeSH Terms
Databases, Genetic Humans Internet Leukemia/genetics
Authors & Affiliations
8 authors, click to expand affiliations / ORCID
Hebestreit Katja
Institute of Medical Informatics, University of Muenster, Muenster. Germany.
Gröttrup Sören
Emden Daniel
Veerkamp Jannis
Ruckert Christian
Klein Hans-Ulrich
Müller-Tidow Carsten
Dugas Martin
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Article Info
Journal
PloS one
Abbr.
PLoS One
ISSN
1932-6203
DOI
10.1371/journal.pone.0039148
Published
2012-00-00
Epub
2012-00-14
Pages
e39148
Language
English
Region
United States
NLM ID
101285081
PMCID
PMC3375295
Subset
IM
External Links
PubMed source DOI: 10.1371/journal.pone.0039148 PMC Full Text View journal details
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