Frequency of glucose-6-phosphate dehydrogenase variants and deficiency in Arabia.

Several variants of G6PD were found in different regions of Saudi Arabia. The variants were separated on the basis of their electrophoretic mobility and activity towards glucose-6-phosphate. G6PD*B was the most common enzyme found in all regions investigated. Variants included G6PD*A, G6PD*A-, G6PD*B weak and G6PD*def. The frequency of the variants shows significant differences among the regions of Saudi Arabia examined.