Home LiteratureArticle Details
PMID: 2285299 Published · ppublish English Journal Article

Ampicillin-resistant enterococcal species in an acute-care hospital.

Antimicrobial agents and chemotherapy ·Vol. 34 ·No. 9 ·1990-09-00 ·Pages 1821-3

Oster SE, Chirurgi VA, Goldberg AA, Aiken S, McCabe RE

Abstract

A prospective review of all enterococcal isolates for 13 months showed that 9.0% were resistant to ampicillin (MIC, greater than or equal to 16 micrograms/ml; zone diameter, less than 15 mm), as determined by the Vitek system, disk diffusion, microdilution MIC testing, and macrodilution MIC testing. All were beta-lactamase negative. A total of 19 and 3 resistant isolates were from urine and intravascular sites, respectively. Ampicillin-resistant enterococci appear to be a growing clinical problem.

MeSH Terms
Adult Aged Aged, 80 and over Ampicillin Resistance/physiology Cross Infection/microbiology Drug Resistance, Microbial Female Gentamicins/pharmacology Humans Male Microbial Sensitivity Tests Microbiological Techniques Middle Aged Streptococcal Infections/drug therapy Streptococcus/drug effects,physiology beta-Lactamases/biosynthesis
Chemicals
Gentamicins beta-Lactamases
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Oster S E
Medical Service, Veterans Administration Medical Center, Martinez, California 94553.
Chirurgi V A
Goldberg A A
Aiken S
McCabe R E
References (14)
14 references, click to expand
  1. Enterococci. Biologic and epidemiologic characteristics and in vitro susceptibility.
    Arch Intern Med. 1982 Oct 25;142(11):2006-9 PMID: 6812524
  2. Enterococcal infections in patients treated with moxalactam.
    Rev Infect Dis. 1982 Nov-Dec;4 Suppl:S708-11 PMID: 6218588
  3. Susceptibilities of enterococci to twelve antibiotics.
    Antimicrob Agents Chemother. 1984 Apr;25(4):532-3 PMID: 6428309
  4. One or two low affinity penicillin-binding proteins may be responsible for the range of susceptibility of Enterococcus faecium to benzylpenicillin.
    J Gen Microbiol. 1985 Aug;131(8):1933-40 PMID: 3850924
  5. In vitro studies of plasmid-mediated penicillinase from Streptococcus faecalis suggest a staphylococcal origin.
    J Clin Invest. 1986 Jan;77(1):289-93 PMID: 3080475
  6. Transition from resistance to hypersusceptibility to beta-lactam antibiotics associated with loss of a low-affinity penicillin-binding protein in a Streptococcus faecium mutant highly resistant to penicillin.
    Antimicrob Agents Chemother. 1985 Nov;28(5):678-83 PMID: 3853962
  7. Species identities of enterococci isolated from clinical specimens.
    J Clin Microbiol. 1990 Mar;28(3):435-7 PMID: 2108992
  8. Comparison of two beta-lactamase-producing strains of Streptococcus faecalis.
    Antimicrob Agents Chemother. 1986 Dec;30(6):861-4 PMID: 3028251
  9. Single-concentration broth microdilution test for detection of high-level aminoglycoside resistance in enterococci.
    J Clin Microbiol. 1987 Dec;25(12):2443-4 PMID: 3123515
  10. Characterization and comparison of two penicillinase-producing strains of Streptococcus (Enterococcus) faecalis.
    Antimicrob Agents Chemother. 1988 Jan;32(1):122-4 PMID: 3126703
  11. High-level penicillin resistance among isolates of enterococci. Implications for treatment of enterococcal infections.
    Ann Intern Med. 1989 Apr 1;110(7):515-20 PMID: 2923386
  12. Identification of Enterococcus species isolated from human infections by a conventional test scheme.
    J Clin Microbiol. 1989 Apr;27(4):731-4 PMID: 2656745
  13. Enterococci highly resistant to penicillin and ampicillin: an emerging clinical problem?
    J Clin Microbiol. 1989 Sep;27(9):2091-5 PMID: 2778072
  14. Susceptibility of enterococci. I. Inhibitory and bactericidal activity of several chemoantibiotics against Streptococcus faecalis and Streptococcus faecium.
    Chemioterapia. 1986 Oct;5(5):302-8 PMID: 3098440
Article Info
Journal
Antimicrobial agents and chemotherapy
Abbr.
Antimicrob Agents Chemother
ISSN
0066-4804
Published
1990-09-00
Pages
1821-3
Language
English
Region
United States
NLM ID
0315061
PMCID
PMC171938
Subset
IM
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]