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PMID: 22940749 Published · ppublish English Journal Article

The International Mouse Phenotyping Consortium: past and future perspectives on mouse phenotyping.

Brown SD, Moore MW

Abstract

Determining the function of all mammalian genes remains a major challenge for the biomedical science community in the 21st century. The goal of the International Mouse Phenotyping Consortium (IMPC) over the next 10 years is to undertake broad-based phenotyping of 20,000 mouse genes, providing an unprecedented insight into mammalian gene function. This short article explores the drivers for large-scale mouse phenotyping and provides an overview of the aims and processes involved in IMPC mouse production and phenotyping.

MeSH Terms
Animals Internationality Mice Mice, Mutant Strains Phenotype
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Brown Steve D M
MRC Mammalian Genetics Unit, MRC Harwell, Oxfordshire OX11 0RD, UK. [email protected]
Moore Mark W
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Article Info
Journal
Mammalian genome : official journal of the International Mammalian Genome Society
Abbr.
Mamm Genome
ISSN
1432-1777
Published
2012-10-00
Epub
2012-00-01
Pages
632-40
Language
English
Region
United States
NLM ID
9100916
PMCID
PMC3774932
Subset
IM
Grants
Medical Research Council · MC_U142684172 · United Kingdom
Medical Research Council · MC_U142684175 · United Kingdom
NIH HHS · U42 OD011174 · United States
NHGRI NIH HHS · U54 HG006348 · United States
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