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PMID: 22973549 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Genetic architecture of migration-related traits in rainbow and steelhead trout, Oncorhynchus mykiss.

G3 (Bethesda, Md.) ·Vol. 2 ·No. 9 ·2012-09-00 ·Pages 1113-27

Hecht BC, Thrower FP, Hale MC, Miller MR, Nichols KM

Abstract

Although migration plays a critical role in the evolution and diversification of species, relatively little is known of the genetic architecture underlying this life history in any species. Rainbow and steelhead trout (Oncorhynchus mykiss) naturally segregate for both resident and migratory life-history types, respectively, as do other members of the salmonid family of fishes. Using an experimental cross derived from wild resident rainbow and wild migratory steelhead trout from Southeast Alaska and high throughput restriction-site associated DNA (RAD) tag sequencing, we perform a quantitative trait locus (QTL) analysis to identify the number, position, and relative contribution of genetic effects on a suite of 27 physiological and morphological traits associated with the migratory life history in this species. In total, 37 QTL are localized to 19 unique QTL positions, explaining 4-13.63% of the variation for 19 of the 27 migration-related traits measured. Two chromosomal positions, one on chromosome Omy12 and the other on Omy14 each harbor 7 QTL for migration-related traits, suggesting that these regions could harbor master genetic controls for the migratory life-history tactic in this species. Another QTL region on Omy5 has been implicated in several studies of adaptive life histories within this species and could represent another important locus underlying the migratory life history. We also evaluate whether loci identified in this out-crossed QTL study colocalize to genomic positions previously identified for associations with migration-related traits in a doubled haploid mapping family.

Keywords
Oncorhynchus mykiss QTL RAD-tag sequencing linkage mapping migration smoltification
MeSH Terms
Animal Migration Animals Body Size/genetics Female Genetic Linkage Genetic Markers Male Oncorhynchus mykiss/anatomy & histology,genetics,physiology Phenotype Physical Chromosome Mapping Quantitative Trait Loci
Chemicals
Genetic Markers
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Hecht Benjamin C
Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907, USA.
Thrower Frank P
Hale Matthew C
Miller Michael R
Nichols Krista M
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Article Info
Journal
G3 (Bethesda, Md.)
Abbr.
G3 (Bethesda)
ISSN
2160-1836
DOI
10.1534/g3.112.003137
Published
2012-09-00
Epub
2012-00-01
Pages
1113-27
Language
English
Region
England
NLM ID
101566598
PMCID
PMC3429926
Subset
IM
External Links
PubMed source DOI: 10.1534/g3.112.003137 PMC Full Text View journal details
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