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PMID: 23193274 Published · ppublish English Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

ENCODE data in the UCSC Genome Browser: year 5 update.

Nucleic acids research ·Vol. 41 ·No. Database issue ·2013-01-00 ·Pages D56-63

Rosenbloom KR, Sloan CA, Malladi VS, Dreszer TR, Learned K, Kirkup VM, Wong MC, Maddren M, Fang R, Heitner SG, Lee BT, Barber GP, Harte RA, Diekhans M, Long JC, Wilder SP, Zweig AS, Karolchik D, Kuhn RM, Haussler D, Kent WJ

Abstract

The Encyclopedia of DNA Elements (ENCODE), http://encodeproject.org, has completed its fifth year of scientific collaboration to create a comprehensive catalog of functional elements in the human genome, and its third year of investigations in the mouse genome. Since the last report in this journal, the ENCODE human data repertoire has grown by 898 new experiments (totaling 2886), accompanied by a major integrative analysis. In the mouse genome, results from 404 new experiments became available this year, increasing the total to 583, collected during the course of the project. The University of California, Santa Cruz, makes this data available on the public Genome Browser http://genome.ucsc.edu for visual browsing and data mining. Download of raw and processed data files are all supported. The ENCODE portal provides specialized tools and information about the ENCODE data sets.

MeSH Terms
Animals Databases, Genetic Genome, Human Genomics Humans Internet Mice Software
Authors & Affiliations
21 authors, click to expand affiliations / ORCID
Rosenbloom Kate R
Center for Biomolecular Science and Engineering, School of Engineering, University of California Santa Cruz (UCSC), Santa Cruz, CA 95064, USA. [email protected]
Sloan Cricket A
Malladi Venkat S
Dreszer Timothy R
Learned Katrina
Kirkup Vanessa M
Wong Matthew C
Maddren Morgan
Fang Ruihua
Heitner Steven G
Lee Brian T
Barber Galt P
Harte Rachel A
Diekhans Mark
Long Jeffrey C
Wilder Steven P
Zweig Ann S
Karolchik Donna
Kuhn Robert M
Haussler David
Kent W James
References (23)
23 references, click to expand
  1. Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors.
    Genome Res. 2012 Sep;22(9):1798-812 PMID: 22955990
  2. PseudoPipe: an automated pseudogene identification pipeline.
    Bioinformatics. 2006 Jun 15;22(12):1437-9 PMID: 16574694
  3. ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia.
    Genome Res. 2012 Sep;22(9):1813-31 PMID: 22955991
  4. Landscape of transcription in human cells.
    Nature. 2012 Sep 6;489(7414):101-8 PMID: 22955620
  5. ENCODE whole-genome data in the UCSC Genome Browser.
    Nucleic Acids Res. 2010 Jan;38(Database issue):D620-5 PMID: 19920125
  6. ChIA-PET tool for comprehensive chromatin interaction analysis with paired-end tag sequencing.
    Genome Biol. 2010;11(2):R22 PMID: 20181287
  7. Retrocopy contributions to the evolution of the human genome.
    BMC Genomics. 2008 Oct 08;9:466 PMID: 18842134
  8. Model-based analysis of ChIP-Seq (MACS).
    Genome Biol. 2008;9(9):R137 PMID: 18798982
  9. Mapping networks of physical interactions between genomic elements using 5C technology.
    Nat Protoc. 2007;2(4):988-1002 PMID: 17446898
  10. Ensembl 2012.
    Nucleic Acids Res. 2012 Jan;40(Database issue):D84-90 PMID: 22086963
  11. The UCSC Genome Browser database: extensions and updates 2011.
    Nucleic Acids Res. 2012 Jan;40(Database issue):D918-23 PMID: 22086951
  12. ENCODE whole-genome data in the UCSC genome browser (2011 update).
    Nucleic Acids Res. 2011 Jan;39(Database issue):D871-5 PMID: 21037257
  13. Unsupervised pattern discovery in human chromatin structure through genomic segmentation.
    Nat Methods. 2012 Mar 18;9(5):473-6 PMID: 22426492
  14. ENCODE whole-genome data in the UCSC Genome Browser: update 2012.
    Nucleic Acids Res. 2012 Jan;40(Database issue):D912-7 PMID: 22075998
  15. Design and analysis of ChIP-seq experiments for DNA-binding proteins.
    Nat Biotechnol. 2008 Dec;26(12):1351-9 PMID: 19029915
  16. PeakSeq enables systematic scoring of ChIP-seq experiments relative to controls.
    Nat Biotechnol. 2009 Jan;27(1):66-75 PMID: 19122651
  17. An integrated encyclopedia of DNA elements in the human genome.
    Nature. 2012 Sep 6;489(7414):57-74 PMID: 22955616
  18. NCBI GEO: archive for functional genomics data sets--10 years on.
    Nucleic Acids Res. 2011 Jan;39(Database issue):D1005-10 PMID: 21097893
  19. The human genome browser at UCSC.
    Genome Res. 2002 Jun;12(6):996-1006 PMID: 12045153
  20. GENCODE: the reference human genome annotation for The ENCODE Project.
    Genome Res. 2012 Sep;22(9):1760-74 PMID: 22955987
  21. ChromHMM: automating chromatin-state discovery and characterization.
    Nat Methods. 2012 Feb 28;9(3):215-6 PMID: 22373907
  22. An encyclopedia of mouse DNA elements (Mouse ENCODE).
    Genome Biol. 2012 Aug 13;13(8):418 PMID: 22889292
  23. The ENCODE (ENCyclopedia Of DNA Elements) Project.
    Science. 2004 Oct 22;306(5696):636-40 PMID: 15499007
Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
1362-4962
Published
2013-01-00
Epub
2012-00-27
Pages
D56-63
Language
English
Region
England
NLM ID
0411011
PMCID
PMC3531152
Subset
IM
Grants
NHGRI NIH HHS · 3P41HG002371-12S1 · United States
Howard Hughes Medical Institute · United States
NHGRI NIH HHS · 5U41HG004568-04 · United States
Wellcome Trust · 095908 · United Kingdom
NHGRI NIH HHS · 3U41HG004568-03S1 · United States
NHGRI NIH HHS · 5P41HG002371-12 · United States
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