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PMID: 23428371 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

Review on CFD simulation in heart with dilated cardiomyopathy and myocardial infarction.

Computers in biology and medicine ·Vol. 43 ·No. 4 ·2013-05-00 ·页码 377-85

Chan BT, Lim E, Chee KH, Abu Osman NA

Abstract

The heart is a sophisticated functional organ that plays a crucial role in the blood circulatory system. Hemodynamics within the heart chamber can be indicative of exert cardiac health. Due to the limitations of current cardiac imaging modalities, computational fluid dynamics (CFD) have been widely used for the purposes of cardiac function assessment and heart disease diagnosis, as they provide detailed insights into the cardiac flow field. An understanding of ventricular hemodynamics and pathological severities can be gained through studies that employ the CFD method. In this research the hemodynamics of two common myocardial diseases, dilated cardiomyopathy (DCM) and myocardial infarction (MI) were investigated, during both the filling phase and the whole cardiac cycle, through a prescribed geometry and fluid structure interaction (FSI) approach. The results of the research indicated that early stage disease identification and the improvement of cardiac assisting devices and therapeutic procedures can be facilitated through the use of the CFD method.

MeSH 主题词
Algorithms Blood Flow Velocity Cardiomyopathy, Dilated/pathology Computer Simulation Heart/physiology Heart Failure/physiopathology Heart Ventricles/physiopathology Hemodynamics Humans Hydrodynamics Models, Cardiovascular Myocardial Infarction/pathology,physiopathology Myocardium/pathology Thrombosis/pathology Ventricular Function, Left/physiology
作者与单位
共 4 位作者,点击展开单位 / ORCID
Chan Bee Ting
Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, 50603 Kuala Lumpur, Malaysia. [email protected]
Lim Einly
Chee Kok Han
Abu Osman Noor Azuan
Article Info
Journal
Computers in biology and medicine
Abbr.
Comput Biol Med
ISSN
1879-0534
Corresponding email
Published
2013-05-00
电子出版
2013-00-18
页码
377-85
Language
English
Country/Region
United States
NLM ID
1250250
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