Home LiteratureArticle Details
PMID: 23668347 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Analysis of the effects of different pulsatile inlet profiles on the hemodynamical properties of blood flow in patient specific carotid artery with stenosis.

Computers in biology and medicine ·Vol. 43 ·No. 6 ·2013-07-00 ·Pages 717-28

Piskin S, Serdar Celebi M

Abstract

In this study the biomechanical characteristics of a realistic carotid artery [3] are studied numerically using different inlet velocity profiles. Several experimental data measured [32] at the common carotid artery are used as inlet boundary conditions. Computation domain is generated using computed tomography (CT) data of a real patient. Three dimensional (3D) transient NS equations are solved, in this actual domain, using the proposed boundary conditions. Effects of different input conditions on the results of simulation are discussed. Main parameters such as velocity profiles, wall shear stress (WSS) and pressure distributions are investigated at the critical parts of the carotid artery such as bifurcation and sinusoidal enlargement regions. Results show that the input boundary conditions and slope/curvature discontinuities in the realistic geometry have strong relationship with the velocity, pressure and WSS distributions as expected. The most important conclusion obtained from our model is the existence of negative relation between velocity at several inner points of the internal carotid artery and velocity at the inlet of the common carotid artery.

MeSH Terms
Blood Flow Velocity Carotid Artery, Common/pathology,physiology Carotid Stenosis/pathology,physiopathology Female Humans Male Models, Cardiovascular Pulsatile Flow
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Piskin Senol
Istanbul Technical University, Informatics Institute, Computational Science and Engineering, Ayazaga Kampusu, Maslak 34469, Istanbul, Turkey. [email protected]
Serdar Celebi M
Article Info
Journal
Computers in biology and medicine
Abbr.
Comput Biol Med
ISSN
1879-0534
Published
2013-07-00
Epub
2013-00-18
Pages
717-28
Language
English
Region
United States
NLM ID
1250250
Subset
IM
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]