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PMID: 23864906 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

CFD modelling of abdominal aortic aneurysm on hemodynamic loads using a realistic geometry with CT.

Computational and mathematical methods in medicine ·Vol. 2013 ·2013-00-00 ·页码 472564

Soudah E, Ng EY, Loong TH, Bordone M, Pua U, Narayanan S

Abstract

The objective of this study is to find a correlation between the abdominal aortic aneurysm (AAA) geometric parameters, wall stress shear (WSS), abdominal flow patterns, intraluminal thrombus (ILT), and AAA arterial wall rupture using computational fluid dynamics (CFD). Real AAA 3D models were created by three-dimensional (3D) reconstruction of in vivo acquired computed tomography (CT) images from 5 patients. Based on 3D AAA models, high quality volume meshes were created using an optimal tetrahedral aspect ratio for the whole domain. In order to quantify the WSS and the recirculation inside the AAA, a 3D CFD using finite elements analysis was used. The CFD computation was performed assuming that the arterial wall is rigid and the blood is considered a homogeneous Newtonian fluid with a density of 1050 kg/m(3) and a kinematic viscosity of 4 × 10(-3) Pa·s. Parallelization procedures were used in order to increase the performance of the CFD calculations. A relation between AAA geometric parameters (asymmetry index ( β ), saccular index ( γ ), deformation diameter ratio ( χ ), and tortuosity index ( ε )) and hemodynamic loads was observed, and it could be used as a potential predictor of AAA arterial wall rupture and potential ILT formation.

MeSH 主题词
Algorithms Aortic Aneurysm, Abdominal/diagnostic imaging,physiopathology Computational Biology Computer Simulation Finite Element Analysis Hemodynamics Humans Hydrodynamics Imaging, Three-Dimensional/methods Male Models, Cardiovascular Radiographic Image Interpretation, Computer-Assisted/methods Stress, Mechanical Tomography, X-Ray Computed/statistics & numerical data
作者与单位
共 6 位作者,点击展开单位 / ORCID
Soudah Eduardo
Centre Internacional de Mètodes Numèrics en Enginyeria, Biomedical Engineering Department, Technical University of Catalonia, C/Gran Capità, s/n, 08034 Barcelona, Spain.
Ng E Y K
Loong T H
Bordone Maurizio
Pua Uei
Narayanan Sriram
Article Info
Journal
Computational and mathematical methods in medicine
Abbr.
Comput Math Methods Med
ISSN
1748-6718
Published
2013-00-00
电子出版
2013-00-24
页码
472564
Language
English
Country/Region
United States
NLM ID
101277751
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