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PMID: 2403534 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't

Evidence for three separate genes encoding the proteins of the mycobacterial antigen 85 complex.

Infection and immunity ·Vol. 58 ·No. 1 ·1990-01-00 ·Pages 272-4

Wiker HG, Sletten K, Nagai S, Harboe M

Abstract

The secreted Mycobacterium bovis BCG antigen 85 complex, which is known to bind to human fibronectin, consists of three closely related cross-reacting antigens. Amino-terminal sequence analysis of the purified proteins showed distinct differences. Data are presented to show that the three components are produced by individual cells, which indicates that three separate genes are involved.

MeSH Terms
Amino Acid Sequence Antigens, Bacterial/genetics Genes, Bacterial Immunoelectrophoresis, Two-Dimensional Macromolecular Substances Molecular Sequence Data Molecular Weight Mycobacterium bovis/genetics,immunology
Chemicals
Antigens, Bacterial Macromolecular Substances
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Wiker H G
Institute of Immunology and Rheumatology, University of Oslo, Norway.
Sletten K
Nagai S
Harboe M
References (21)
21 references, click to expand
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Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/iai.58.1.272-274.1990
Published
1990-01-00
Pages
272-4
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC258444
Subset
IM
External Links
PubMed source DOI: 10.1128/iai.58.1.272-274.1990 PMC Full Text View journal details
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