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PMID: 24109785 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Numerical simulation and hemodynamic analysis of the modified Blalock-Taussig shunt.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference ·Vol. 2013 ·2013-00-00 ·页码 707-10

Liu J, Sun Q, Qian Y, Hong H, Liu J

Abstract

The modified Blalock-Taussig (mB-T) shunt is an effective palliative surgical method in the treatment of cyanotic congenital heart diseases. It increases the pulmonary blood flow through an implanted shunt between systemic and pulmonary arteries. The surgical technique improved over the years. However, it is still a challenge to control appropriate distribution of blood flow through this shunt after this kind of procedure till now. Here, we report on the method of computational fluid dynamics (CFD) for the hemodynamic studies of a patient-specific case after the mB-T shunt. The analysis system that we validated previously in the studies of the Norwood procedure was applied to predict the hemodynamic characteristics in the mB-T hunt area. The real-time velocities derived from Echocardiography measurements and the blood pressure wave reflections from peripheral vessels were utilized as boundary conditions to physiologically capture the blood flow information in the simulation. The local pressure, blood flow distribution and wall shear stress were calculated. The results suggest pressure decreases greatly through the shunt and around 40% of blood flow is distributed from the systemic circulation to pulmonary arteries in one cardiac cycle. These indict computational hemodynamics may be applied in future studies of establishing quantitative standards to evaluate the outcomes of the mB-T shunt and to optimize the implantation of the mB-T shunt in virtual surgeries.

MeSH 主题词
Blalock-Taussig Procedure Computer Simulation Heart Defects, Congenital/physiopathology,surgery Hemodynamics Humans Hydrodynamics Infant Models, Cardiovascular Pulmonary Artery/physiopathology,surgery
作者与单位
共 5 位作者,点击展开单位 / ORCID
Liu Jinlong
Sun Qi
Qian Yi
Hong Haifa
Liu Jinfen
Article Info
Journal
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Abbr.
Annu Int Conf IEEE Eng Med Biol Soc
ISSN
2694-0604
Published
2013-00-00
页码
707-10
Language
English
Country/Region
United States
NLM ID
101763872
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