Home LiteratureArticle Details

PMID: 2415260 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Vascular outgrowths from tissue explants embedded in fibrin or collagen gels: a simple in vitro model of angiogenesis.

Cell biology international reports ·Vol. 9 ·No. 10 ·1985-10-00 ·Pages 869-75

Montesano R, Mouron P, Orci L

Abstract

Explants of muscular and adipose tissue embedded in a three-dimensional matrix of fibrin or collagen fibrils give rise to an extensive outgrowth of branching and anastomosing capillary-like tubes. This culture system provides a simple in vitro model for the study of angiogenesis.

MeSH Terms

Adipose Tissue/blood supply Animals Capillaries/physiology Cell Survival Collagen Culture Media Culture Techniques/methods Endothelium/physiology Fibrin Gels Muscles/blood supply Neovascularization, Pathologic/physiopathology Rats Time Factors

Chemicals

Culture Media Gels Fibrin Collagen

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Montesano R

Mouron P

Orci L

Article Info

Journal

Cell biology international reports

Abbr.

Cell Biol Int Rep

ISSN

0309-1651

DOI

10.1016/s0309-1651(85)90107-9

Published

1985-10-00

Pages

869-75

Language

English

Region

England

NLM ID

7708050

Subset

External Links

PubMed source DOI: 10.1016/s0309-1651(85)90107-9

Analysis Services

Vascular outgrowths from tissue explants embedded in fibrin or collagen gels: a simple in vitro model of angiogenesis.

Contact

WeChat Official Account