Home LiteratureArticle Details
PMID: 2419568 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S. Review

Gating of sodium and potassium channels.

The Journal of membrane biology ·Vol. 88 ·No. 2 ·1985-00-00 ·Pages 97-111

Bezanilla F

Abstract

暂无摘要

MeSH Terms
Adenosine Triphosphate/pharmacology Animals Axons/physiology Cell Membrane/physiology Decapodiformes Electric Conductivity Ion Channels/analysis Mathematics Membrane Potentials Models, Neurological Potassium/analysis Protein Conformation Reaction Time Sodium/analysis
Chemicals
Ion Channels Adenosine Triphosphate Sodium Potassium
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Bezanilla F
References (48)
48 references, click to expand
  1. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches.
    Pflugers Arch. 1981 Aug;391(2):85-100 PMID: 6270629
  2. Statistical properties of single sodium channels.
    J Gen Physiol. 1984 Oct;84(4):505-34 PMID: 6094703
  3. Gating current and potassium channels in the giant axon of the squid.
    Biophys J. 1980 Mar;29(3):485-92 PMID: 6271271
  4. Sodium channel gating: models, mimics, and modifiers.
    Annu Rev Biophys Bioeng. 1983;12:319-56 PMID: 6307117
  5. Sodium channels and gating currents.
    Physiol Rev. 1981 Jul;61(3):644-83 PMID: 6265962
  6. Sodium channel activation in the squid giant axon. Steady state properties.
    J Gen Physiol. 1985 Jan;85(1):65-82 PMID: 2578549
  7. Single Na+ channel currents observed in cultured rat muscle cells.
    Nature. 1980 Oct 2;287(5781):447-9 PMID: 6253802
  8. A reinterpretation of mammalian sodium channel gating based on single channel recording.
    Nature. 1983 Dec 1-7;306(5942):436-41 PMID: 6316158
  9. Some kinetic and steady-state properties of sodium channels after removal of inactivation.
    J Gen Physiol. 1981 Jan;77(1):1-22 PMID: 6162910
  10. Sodium and potassium currents in squid axons perfused with fluoride solutions.
    J Physiol. 1970 Dec;211(3):623-52 PMID: 5501055
  11. Activation of squid axon K+ channels. Ionic and gating current studies.
    J Gen Physiol. 1985 Apr;85(4):539-54 PMID: 2409218
  12. Analysis of certain errors in squid axon voltage clamp measurements.
    Biophys J. 1960 Nov;1:161-202 PMID: 13775643
  13. Single channel recordings of K+ currents in squid axons.
    Nature. 1980 May 15;285(5761):140-3 PMID: 6246440
  14. Gating currents associated with potassium channel activation.
    Nature. 1982 Apr 15;296(5858):657-9 PMID: 6280059
  15. Destruction of sodium conductance inactivation in squid axons perfused with pronase.
    J Gen Physiol. 1973 Oct;62(4):375-91 PMID: 4755846
  16. Protein components of the purified sodium channel from rat skeletal muscle sarcolemma.
    J Neurochem. 1983 May;40(5):1377-85 PMID: 6300333
  17. Effect of N-bromoacetamide on single sodium channel currents in excised membrane patches.
    J Gen Physiol. 1982 Mar;79(3):333-51 PMID: 6281357
  18. Sodium and gating current time shifts resulting from changes in initial conditions.
    J Gen Physiol. 1983 Jun;81(6):773-84 PMID: 6308124
  19. Potential energy barriers to ion transport within lipid bilayers. Studies with tetraphenylborate.
    Biophys J. 1975 Aug;15(8):795-830 PMID: 1148364
  20. Kinetic properties and inactivation of the gating currents of sodium channels in squid axon.
    Philos Trans R Soc Lond B Biol Sci. 1975 Jun 10;270(908):449-58 PMID: 238241
  21. Inactivation of the asymmetrical displacement current in giant axons of Loligo forbesi.
    J Physiol. 1977 May;267(2):377-93 PMID: 874869
  22. The components of membrane conductance in the giant axon of Loligo.
    J Physiol. 1952 Apr;116(4):473-96 PMID: 14946714
  23. Survival of K+ permeability and gating currents in squid axons perfused with K+-free media.
    J Gen Physiol. 1980 Jan;75(1):61-78 PMID: 7359118
  24. Inactivation of the sodium current in Myxicola giant axons. Evidence for coupling to the activation process.
    J Gen Physiol. 1972 Jun;59(6):659-75 PMID: 5025744
  25. Fast and slow steps in the activation of sodium channels.
    J Gen Physiol. 1979 Dec;74(6):691-711 PMID: 536736
  26. Charge movement associated with the opening and closing of the activation gates of the Na channels.
    J Gen Physiol. 1974 May;63(5):533-52 PMID: 4824995
  27. The dual effect of membrane potential on sodium conductance in the giant axon of Loligo.
    J Physiol. 1952 Apr;116(4):497-506 PMID: 14946715
  28. Fractionation of the asymmetry current in the squid giant axon into inactivating and non-inactivating components.
    Proc R Soc Lond B Biol Sci. 1982 Jun 22;215(1200):375-89 PMID: 6127712
  29. The after-effects of impulses in the giant nerve fibres of Loligo.
    J Physiol. 1956 Feb 28;131(2):341-76 PMID: 13320339
  30. A quantitative description of membrane current and its application to conduction and excitation in nerve.
    J Physiol. 1952 Aug;117(4):500-44 PMID: 12991237
  31. Single-channel properties of the reconstituted voltage-regulated Na channel isolated from the electroplax of Electrophorus electricus.
    Proc Natl Acad Sci U S A. 1984 Sep;81(17):5594-8 PMID: 6089214
  32. Primary structure of Electrophorus electricus sodium channel deduced from cDNA sequence.
    Nature. 1984 Nov 8-14;312(5990):121-7 PMID: 6209577
  33. Inactivation of the sodium channel. II. Gating current experiments.
    J Gen Physiol. 1977 Nov;70(5):567-90 PMID: 591912
  34. The temporal and steady-state relationships between activation of the sodium conductance and movement of the gating particles in the squid giant axon.
    J Physiol. 1976 Feb;255(1):157-89 PMID: 1255514
  35. A slow component of gating current in crayfish giant axons resembles inactivation charge movement.
    Biophys J. 1983 Mar;41(3):245-9 PMID: 6301570
  36. The Croonian Lecture, 1983. Voltage-gated ion channels in the nerve membrane.
    Proc R Soc Lond B Biol Sci. 1983 Nov 22;220(1218):1-30 PMID: 6140679
  37. Binding of radioactively labeled saxitoxin to the squid giant axon.
    J Membr Biol. 1979 Aug;48(4):357-64 PMID: 490630
  38. Effect of chloroform on charge movement in the nerve membrane.
    Nature. 1982 May 13;297(5862):150-2 PMID: 6281652
  39. The binding of tritiated tetrodotoxin to squid giant axons.
    Philos Trans R Soc Lond B Biol Sci. 1975 Jun 10;270(908):349-52 PMID: 238233
  40. Initial conditions and the kinetics of the sodium conductance in Myxicola giant axons. I. effects on the time-course of the sodium conductance.
    J Gen Physiol. 1978 Dec;72(6):863-77 PMID: 731202
  41. Gating currents and charge movements in excitable membranes.
    Rev Physiol Biochem Pharmacol. 1978;82:96-190 PMID: 356157
  42. Currents associated with the ionic gating structures in nerve membrane.
    Ann N Y Acad Sci. 1975 Dec 30;264:265-77 PMID: 1062958
  43. Statistical analysis of single sodium channels. Effects of N-bromoacetamide.
    Biophys J. 1984 Jan;45(1):323-35 PMID: 6324912
  44. Inactivation of the sodium channel. I. Sodium current experiments.
    J Gen Physiol. 1977 Nov;70(5):549-66 PMID: 591911
  45. Inactivation viewed through single sodium channels.
    J Gen Physiol. 1984 Oct;84(4):535-64 PMID: 6094704
  46. Relations between the inactivation of sodium channels and the immobilization of gating charge in frog myelinated nerve.
    J Physiol. 1980 Feb;299:573-603 PMID: 6247484
  47. Properties of the sodium channel gating current.
    Cold Spring Harb Symp Quant Biol. 1976;40:297-304 PMID: 1065531
  48. Pressure dependence of sodium gating currents in the squid giant axon.
    Eur Biophys J. 1984;11(2):137-47 PMID: 6100544
Article Info
Journal
The Journal of membrane biology
Abbr.
J Membr Biol
ISSN
0022-2631
DOI
10.1007/BF01868424
Published
1985-00-00
Pages
97-111
Language
English
Region
United States
NLM ID
0211301
Subset
IM
Grants
NIGMS NIH HHS · GM 30376 · United States
External Links
PubMed source DOI: 10.1007/BF01868424 View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2