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PMID: 2420585 Published · ppublish English Journal Article Review

Micellar enzymology.

European journal of biochemistry ·Vol. 155 ·No. 3 ·1986-03-17 ·Pages 453-68

Martinek K, Levashov AV, Klyachko N, Khmelnitski YL, Berezin IV

Abstract

Experimental approaches to modelling the enzymatic function of biological membranes are discussed. Emphasis is given to pseudohomogeneous systems such as proteolipid complexes and enzymes in organic solvents; the latter are solubilized with phospholipids or synthetic surfactants. Methods for producing and studying such micellar systems are considered. The key research problems of micellar enzymology are formulated and its relation to enzyme membranology is discussed. Finally, the new potentialities are noted of applied enzymology (biotechnology) offered by application of a colloidal solution of water in organic solvents as a microheterogeneous medium for enzymatic reactions.

MeSH Terms
Catalysis Colloids Dioctyl Sulfosuccinic Acid Enzymes/metabolism Hydrocarbons Kinetics Lipid Bilayers Lipolysis Membranes/enzymology Micelles Models, Chemical Molecular Weight Oxidation-Reduction Phospholipids Rhodopsin Solubility Solvents Substrate Specificity Surface-Active Agents Water
Chemicals
Colloids Enzymes Hydrocarbons Lipid Bilayers Micelles Phospholipids Solvents Surface-Active Agents Water Dioctyl Sulfosuccinic Acid Rhodopsin
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Martinek K
Levashov A V
Klyachko N
Khmelnitski Y L
Berezin I V
Article Info
Journal
European journal of biochemistry
Abbr.
Eur J Biochem
ISSN
0014-2956
Published
1986-03-17
Pages
453-68
Language
English
Region
England
NLM ID
0107600
Subset
IM
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