Nonintercalating DNA-binding ligands: specificity of the interaction and their use as tools in biophysical, biochemical and biological investigations of the genetic material.

Aminoglycosides Animals Anthramycin/metabolism Antibiotics, Antineoplastic/metabolism Base Sequence Binding Sites Bisbenzimidazole/metabolism Cattle Centrifugation, Density Gradient Chemical Phenomena Chemistry, Physical Chromosomes/analysis Circular Dichroism DNA/analysis,biosynthesis,metabolism DNA, Superhelical/metabolism Diminazene/analogs & derivatives,metabolism Distamycins/metabolism Drug Interactions Duocarmycins Indoles Leucomycins/metabolism Ligands Magnetic Resonance Spectroscopy Mathematics Models, Molecular Netropsin/metabolism Plicamycin/metabolism Protein Conformation Pyridinium Compounds/metabolism RNA/biosynthesis,metabolism Spectrophotometry, Ultraviolet Staining and Labeling Thermodynamics

Aminoglycosides Antibiotics, Antineoplastic DNA, Superhelical Distamycins Duocarmycins Indoles Leucomycins Ligands Pyridinium Compounds Anthramycin sibiromycin NSC 101327 RNA Netropsin CC 1065 stallimycin DNA diminazene aceturate Bisbenzimidazole Plicamycin Diminazene