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PMID: 2431705 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

In vivo induction of Ia antigens on rat keratinocytes by gamma-interferon.

The British journal of dermatology ·Vol. 115 ·No. 5 ·1986-11-00 ·Pages 543-9

Scheynius A, Johansson C, van der Meide PH

Abstract

Recombinant rat IFN-gamma was found to induce Ia antigen expression on rat keratinocytes in vivo. Strong expression of Ia antigen on keratinocytes of rat ears was produced after intradermal injections of 10,000 U IFN-gamma once daily on 3 successive days. The expression was still pronounced 2 days after the last injection, but had disappeared 4 days later.

MeSH Terms
Animals Cell Movement Epidermal Cells Epidermis/immunology Histocompatibility Antigens Class II/analysis Immunoenzyme Techniques Interferon-gamma/pharmacology Keratins/immunology Rats Rats, Inbred Strains
Chemicals
Histocompatibility Antigens Class II Keratins Interferon-gamma
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Scheynius A
Johansson C
van der Meide P H
Article Info
Journal
The British journal of dermatology
Abbr.
Br J Dermatol
ISSN
0007-0963
DOI
10.1111/j.1365-2133.1986.tb05763.x
Published
1986-11-00
Pages
543-9
Language
English
Region
England
NLM ID
0004041
Subset
IM
External Links
PubMed source DOI: 10.1111/j.1365-2133.1986.tb05763.x View journal details
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