Home LiteratureArticle Details
PMID: 24419544 Published · ppublish English Journal Article

Proposals to the problem of structural and functional organization of polytene chromosomes.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik ·Vol. 45 ·No. 8 ·1974-01-00 ·Pages 335-40

Zhimulev IF, Belyaeva ES

Abstract

The concept of the structural and functional organization of polytene chromosomes is formulated. It is based on the following:Interbands are transcriptional active chromosome regions; they seem to be responsible for the base metabolism of the cell. The stability of these metabolic processes in the cells of different organs results in constancy of chromosome banding pattern. Thus, each functional state of the cell possesses its own banding pattern which may vary depending on activity level and degree of condensation of interbands.The band is considered not as a structural or functional unit, but as a region of the chromosome not involved in transcription at a certain point of time; a band may contain one or several genes.

Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Zhimulev I F
Institute of Cytology and Genetics, Novosibirsk, U.S.S.R..
Belyaeva E S
References (38)
38 references, click to expand
  1. Relation of puffing to bristle and footpad differentiation in Calliphora and Sarcophaga.
    Results Probl Cell Differ. 1972;4:153-79 PMID: 4579363
  2. Changes in chromosomes induced by microorganism infection.
    Proc Natl Acad Sci U S A. 1965 Nov;54(5):1321-7 PMID: 5218253
  3. Comparative study of the function of polytene chromosomes in laboratory stocks of Drosophila melanogaster and the l(3)tl mutant (lethal tumorous larvae). I. Analysis of puffing patterns in autosomes of the laboratory stock Batumi-L.
    Chromosoma. 1974 May 21;46(1):59-76 PMID: 4210096
  4. Chromosomal organization as a genetic basis of cytodifferentiation in multicellular organisms.
    Nature. 1965 May 15;206(985):742-4 PMID: 5319425
  5. Characterization of the genome of the cellular slime mold Dictyostelium discoideum.
    J Mol Biol. 1972 May 28;66(3):339-61 PMID: 4556574
  6. General theory of chromosome structure and gene activation in eukaryotes.
    Nature. 1972 Aug 25;238(5365):444-6 PMID: 4561852
  7. STRUCTURAL AND PHENOTYPIC DEFINITION OF THE ROSY CISTRON IN DROSOPHILA MELANOGASTER.
    Genetics. 1964 Dec;50:1261-8 PMID: 14239786
  8. Comparative ultrastructural study of perichromatin- and Balbiai rin granules.
    J Ultrastruct Res. 1971 Sep;36(5):842-60 PMID: 4108513
  9. Synthesis of RNA in the left arm of the third chromosome of Drosophila melanogaster in the last five hours of larval development.
    Sov J Dev Biol. 1972 May-Jun;3(3):230-7 PMID: 4633088
  10. [Alterations in puffing pattern and growth of giant chromosomes in salivary glands from late larval and embryonic donors after culture in vivo].
    Chromosoma. 1969;26(1):76-104 PMID: 5799424
  11. On estimating functional gene number in eukaryotes.
    Nat New Biol. 1973 Mar 14;242(115):52-4 PMID: 4512011
  12. [GROWTH TO EXTENSIVE SIZE OF LARVAL SALIVARY GLAND CHROMOSOMES OF DROSOPHILA MELANOGASTER IN ADULT MILIEU].
    Experientia. 1963 Oct 15;19:530-1 PMID: 14094060
  13. ANALYSIS OF CHROMOSOME 4 IN DROSOPHILA MELANOGASTER. I. SPONTANEOUS AND X-RAY-INDUCED LETHALS.
    Genetica. 1964;35:109-26 PMID: 14170379
  14. Size and distribution of the repetitive segments of the Drosophila genome.
    J Mol Biol. 1972 Feb 28;64(1):211-9 PMID: 4622630
  15. General model for the chromosomes of higher organisms.
    Nature. 1971 Nov 5;234(5323):25-7 PMID: 4942881
  16. Analysis of chromosome 4 in Drosophila melanogaster. II. Ethyl methanesulfonate induced lethals.
    Genetics. 1971 Feb;67(2):235-52 PMID: 5569209
  17. Diversity of RNA sequences in Drosophila melanogaster.
    Biochem Genet. 1973 Nov;10(3):263-74 PMID: 4201856
  18. Molecular characterization of the Drosophila genome.
    Genetics. 1969 Dec;63(4):865-82 PMID: 4922975
  19. Time sequence in the expression of various developmental characters induced by ecdysterone in Drosophila hydei.
    Dev Biol. 1970 Oct;23(2):210-25 PMID: 4248971
  20. Changes in the expression of single-copy DNA during development of the cellular slime mold Dictyostelium discoideum.
    J Mol Biol. 1972 May 28;66(3):363-77 PMID: 5064459
  21. Cytogenetic fine structure and chromosomal localization of the white gene in Drosophila melanogaster.
    Nat New Biol. 1973 Sep 12;245(141):34-7 PMID: 4125726
  22. PSEUDO-ALLELISM AT THE VERMILION LOCUS IN DROSOPHILA MELANOGASTER.
    Proc Natl Acad Sci U S A. 1954 Feb;40(2):92-9 PMID: 16589441
  23. A replicative and synthetic chromosomal unit--the modern concept of the chromomere.
    Proc R Soc Lond B Biol Sci. 1966 Mar 22;164(995):279-89 PMID: 4379517
  24. A small nuclear precursor of messenger RNA in the cellular slime mold Dictyostelium discoideum.
    J Mol Biol. 1973 Sep 15;79(2):295-314 PMID: 4796769
  25. Mucopolysaccharide secretion from Drosophila salivary gland cells as a consequence of hormone induced gene activity.
    Cell Differ. 1972 Jun;1(2):63-78 PMID: 4275743
  26. Salivary chromosome bands and the frequency of crossing over in Drosophila melanogaster.
    Genetics. 1971 Apr;67(4):497-513 PMID: 4999628
  27. Some observations on the distribution and molecular arrangement of nucleic acids in salivary gland nuclei of Drosophila melanogaster.
    Can J Genet Cytol. 1973 Sep;15(3):509-22 PMID: 4128468
  28. Behavior of polytene chromosomes "in vitro".
    Genetics. 1969;61(1):Suppl:361-72 PMID: 5345393
  29. [Electron microscopic study of polytene chromosomes in the salivary glands of Chironomus plumosus larvae].
    Dokl Akad Nauk SSSR. 1971 Feb 21;196(6):1452-5 PMID: 5576305
  30. [Chromomore constancy and specific modifications of the chromosome structure in development and organ differentiation of Chironomus tentans].
    Chromosoma. 1952;5(2):Unknown PMID: 13067187
  31. The DNA content of sperm of Drosophila melanogaster.
    Chromosoma. 1971;33(1):1-18 PMID: 5574762
  32. Salivary gland function and chromosomal puffing patterns in Drosophila hydei.
    Chromosoma. 1965;17(1):35-77 PMID: 5833949
  33. The anatomy and function of a segment of the X chromosome of Drosophila melanogaster.
    Genetics. 1972 May;71(1):139-56 PMID: 4624778
  34. THE STRUCTURE OF THE CHROMOSOMES IN THE SALIVARY GLANDS OF DROSOPHILA.
    Science. 1934 Oct 5;80(2075):312-3 PMID: 17769043
  35. Ecdysone induction of puffing activity in salivary glands ofDrosophila melanogaster grown in adult abdomens.
    Wilhelm Roux Arch Entwickl Mech Org. 1973 Jun;172(2):166-170 PMID: 28304590
  36. SYNTHESIS OF MESSENGER RNA ON THE POLYTENE CHROMOSOMES OF DIPTERAN SALIVARY GLAND.
    Nature. 1963 Nov 2;200:494-5 PMID: 14076758
  37. [A hypothesis on the functional organization of the chromosomes of higher organisms].
    Theor Appl Genet. 1974 Jan;44(3):97-9 PMID: 24425425
  38. Polytene chromosome structure at the submicroscopic level. I. A map of region X, 1--4E of Drosophila melanogaster.
    Chromosoma. 1970;29(1):118-30 PMID: 5415219
Article Info
Journal
TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik
Abbr.
Theor Appl Genet
ISSN
0040-5752
DOI
10.1007/BF00277673
Published
1974-01-00
Pages
335-40
Language
English
Region
Germany
NLM ID
0145600
External Links
PubMed source DOI: 10.1007/BF00277673 View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2